ethyl (2R)-2-(1-benzyl-1H-indol-3-yl)-3,3,3-trifluoro-2-hydroxypropanoate

Base Information

Chemical Name:ethyl (2R)-2-(1-benzyl-1H-indol-3-yl)-3,3,3-trifluoro-2-hydroxypropanoate
CAS No.:1296864-40-8
Molecular Formula:C₂₀H₁₈F₃NO₃
Molecular Weight:377.363
Hs Code.:

Synonyms:ethyl (2R)-2-(1-benzyl-1H-indol-3-yl)-3,3,3-trifluoro-2-hydroxypropanoate

Suppliers and Price of ethyl (2R)-2-(1-benzyl-1H-indol-3-yl)-3,3,3-trifluoro-2-hydroxypropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl (2R)-2-(1-benzyl-1H-indol-3-yl)-3,3,3-trifluoro-2-hydroxypropanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl (2R)-2-(1-benzyl-1H-indol-3-yl)-3,3,3-trifluoro-2-hydroxypropanoate

There total 2 articles about ethyl (2R)-2-(1-benzyl-1H-indol-3-yl)-3,3,3-trifluoro-2-hydroxypropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 3377-71-7
N-benzylindole

: 13081-18-0
ethyl-3,3,3-trifluoropyruvate

: 1296864-40-8
ethyl (2R)-2-(1-benzyl-1H-indol-3-yl)-3,3,3-trifluoro-2-hydroxypropanoate

Guidance literature:: ethyl-3,3,3-trifluoropyruvate; With copper (I) trifluoromethane sulfonate toluene complex; C₂₄H₂₆N₂O₂; In diethyl ether; at -98 - 20 ℃; for 0.333333h; Inert atmosphere;

N-benzylindole; In diethyl ether; at -98 ℃; for 2h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1002/adsc.201000918

Reference yield:

: 3377-71-7
N-benzylindole

: 13081-18-0
ethyl-3,3,3-trifluoropyruvate

: ethyl (2S)-2-(1-benzyl-1H-indol-3-yl)-3,3,3-trifluoro-2-hydroxypropanoate

: 1296864-40-8
ethyl (2R)-2-(1-benzyl-1H-indol-3-yl)-3,3,3-trifluoro-2-hydroxypropanoate

Guidance literature:: ethyl-3,3,3-trifluoropyruvate; With copper (I) trifluoromethane sulfonate toluene complex; C₂₄H₂₆N₂O₂; In diethyl ether; at -78 - 20 ℃; for 0.333333h; Inert atmosphere;

N-benzylindole; In diethyl ether; at -78 ℃; for 2h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1002/adsc.201000918