(+/-)-N-[2-[[[[2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-amino]-1-phenylethyl]-2-quinolylamide

Base Information

Chemical Name:(+/-)-N-[2-[[[[2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-amino]-1-phenylethyl]-2-quinolylamide
CAS No.:155273-74-8
Molecular Formula:C₃₁H₃₄N₄O₂
Molecular Weight:494.637
Hs Code.:

Synonyms:(+/-)-N-[2-[[[[2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-amino]-1-phenylethyl]-2-quinolylamide

Suppliers and Price of (+/-)-N-[2-[[[[2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-amino]-1-phenylethyl]-2-quinolylamide

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Chemical Property of (+/-)-N-[2-[[[[2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-amino]-1-phenylethyl]-2-quinolylamide

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Technology Process of (+/-)-N-[2-[[[[2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-amino]-1-phenylethyl]-2-quinolylamide

There total 4 articles about (+/-)-N-[2-[[[[2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-amino]-1-phenylethyl]-2-quinolylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 93-10-7,1199266-78-8
quinoline-2-carboxylic acid

: 155273-74-8
(+/-)-N-[2-[[[[2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-amino]-1-phenylethyl]-2-quinolylamide

Guidance literature:: Multi-step reaction with 3 steps

1: 1,1'-carbonyldiimidazole / tetrahydrofuran / 24 h / Ambient temperature

2: NH₃, H₂ / Ranney nickel / methanol / 2585.7 Torr / Ambient temperature

3: tetrahydrofuran / 2 h / Ambient temperature

With ammonia; hydrogen; 1,1'-carbonyldiimidazole; ranney nickel; In tetrahydrofuran; methanol;
DOI:10.1021/jm00038a010

Reference yield:

: 16750-42-8,41804-94-8
2-amino-2-phenylacetonitrile

: 155273-74-8
(+/-)-N-[2-[[[[2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-amino]-1-phenylethyl]-2-quinolylamide

Guidance literature:: Multi-step reaction with 3 steps

1: 1,1'-carbonyldiimidazole / tetrahydrofuran / 24 h / Ambient temperature

2: NH₃, H₂ / Ranney nickel / methanol / 2585.7 Torr / Ambient temperature

3: tetrahydrofuran / 2 h / Ambient temperature

With ammonia; hydrogen; 1,1'-carbonyldiimidazole; ranney nickel; In tetrahydrofuran; methanol;
DOI:10.1021/jm00038a010

Reference yield:

: 118880-89-0
Quinoline-2-carboxylic acid (cyano-phenyl-methyl)-amide

: 155273-74-8
(+/-)-N-[2-[[[[2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-amino]-1-phenylethyl]-2-quinolylamide

Guidance literature:: Multi-step reaction with 2 steps

1: NH₃, H₂ / Ranney nickel / methanol / 2585.7 Torr / Ambient temperature

2: tetrahydrofuran / 2 h / Ambient temperature

With ammonia; hydrogen; ranney nickel; In tetrahydrofuran; methanol;
DOI:10.1021/jm00038a010