(4S)-5-[(4R,6R)-4-((E)-2-phenylethenyl)-2,2-dimethyl-1,3-dioxan-6-yl]-4-p-methoxybenzyloxy-2-pentene

Base Information

• Chemical Name: (4S)-5-[(4R,6R)-4-((E)-2-phenylethenyl)-2,2-dimethyl-1,3-dioxan-6-yl]-4-p-methoxybenzyloxy-2-pentene
• CAS No.: 322428-47-7
• Molecular Formula: C₂₇H₃₄O₄
• Molecular Weight: 422.565
• Mol file: 322428-47-7.mol

Synonyms:(4S)-5-[(4R,6R)-4-((E)-2-phenylethenyl)-2,2-dimethyl-1,3-dioxan-6-yl]-4-p-methoxybenzyloxy-2-pentene

Chemical Property of (4S)-5-[(4R,6R)-4-((E)-2-phenylethenyl)-2,2-dimethyl-1,3-dioxan-6-yl]-4-p-methoxybenzyloxy-2-pentene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4S)-5-[(4R,6R)-4-((E)-2-phenylethenyl)-2,2-dimethyl-1,3-dioxan-6-yl]-4-p-methoxybenzyloxy-2-pentene

There total 2 articles about (4S)-5-[(4R,6R)-4-((E)-2-phenylethenyl)-2,2-dimethyl-1,3-dioxan-6-yl]-4-p-methoxybenzyloxy-2-pentene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

2,2-dimethoxy-propane (77-76-9) + (E)-(S)-7-(4-Methoxy-benzyloxy)-1-phenyl-deca-1,9-diene-3,5-diol → (4S)-5-[(4R,6R)-4-((E)-2-phenylethenyl)-2,2-dimethyl-1,3-dioxan-6-yl]-4-p-methoxybenzyloxy-2-pentene (322428-47-7) + (4S)-5-[(4S,6S)-4-((E)-2-phenylethenyl)-2,2-dimethyl-1,3-dioxan-6-yl]-4-p-methoxybenzyloxy-2-pentene

Guidance literature:

With pyridinium p-toluenesulfonate; for 47h;

DOI:10.1016/S0040-4020(01)00593-2

Reference yield:

(E)-(S)-7-(4-Methoxy-benzyloxy)-1-phenyl-deca-1,9-diene-3,5-diol + 2,2-dimethoxy-propane (77-76-9) → (4S)-5-[(4R,6R)-4-((E)-2-phenylethenyl)-2,2-dimethyl-1,3-dioxan-6-yl]-4-p-methoxybenzyloxy-2-pentene (322428-47-7) + (4S)-5-[(4S,6S)-4-((E)-2-phenylethenyl)-2,2-dimethyl-1,3-dioxan-6-yl]-4-p-methoxybenzyloxy-2-pentene

Guidance literature:

With pyridinium p-toluenesulfonate; for 47h;

DOI:10.1021/ol000305i

Reference yield: 77.0%

(4S)-5-[(4R,6R)-4-((E)-2-phenylethenyl)-2,2-dimethyl-1,3-dioxan-6-yl]-4-p-methoxybenzyloxy-2-pentene (322428-47-7) → (4R)-5-[(4R,6R)-4-((E)-2-phenylethenyl)-2,2-dimethyl-1,3-dioxan-6-yl]-4-p-methoxybenzyloxy-2-pentanone (322428-33-1)

Guidance literature:

With copper diacetate; oxygen; palladium dichloride; In N,N-dimethyl acetamide; water; at 20 ℃; for 19.5h;

DOI:10.1016/S0040-4020(01)00593-2

upstream raw materials:

2,2-dimethoxy-propane

Downstream raw materials:

(4R)-5-[(4R,6R)-4-((E)-2-phenylethenyl)-2,2-dimethyl-1,3-dioxan-6-yl]-4-p-methoxybenzyloxy-2-pentanone

(R)-2-Methoxy-3-[(2R,4R,6R)-6-methoxy-4-(4-methoxy-benzyloxy)-6-methyl-tetrahydro-pyran-2-yl]-propionaldehyde

(3R)-4-[(2R,4R,6R)-4-p-methoxybenzyloxy-2-methoxy-2-methyl-tetrahydropyran-6-yl]-3-hydroxy-1-butene

(R)-3-Methoxy-4-[(2R,4R,6R)-6-methoxy-4-(4-methoxy-benzyloxy)-6-methyl-tetrahydro-pyran-2-yl]-butane-1,2-diol