methyl 4-<2-<5--2-(N-methylamino)phenyl>-2-(acetoxyimino)ethyl>-3-methoxybenzoate

Base Information

Chemical Name:methyl 4-<2-<5--2-(N-methylamino)phenyl>-2-(acetoxyimino)ethyl>-3-methoxybenzoate
CAS No.:110707-77-2
Molecular Formula:C₂₇H₃₃N₃O₆
Molecular Weight:495.576
Hs Code.:

methyl 4-<2-<5-<N-(cyclopentylmethyl)carbamoyl>-2-(N-methylamino)phenyl>-2-(acetoxyimino)ethyl>-3-methoxybenzoate

Synonyms:methyl 4-<2-<5--2-(N-methylamino)phenyl>-2-(acetoxyimino)ethyl>-3-methoxybenzoate

Suppliers and Price of methyl 4-<2-<5--2-(N-methylamino)phenyl>-2-(acetoxyimino)ethyl>-3-methoxybenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 4-<2-<5--2-(N-methylamino)phenyl>-2-(acetoxyimino)ethyl>-3-methoxybenzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 4-<2-<5--2-(N-methylamino)phenyl>-2-(acetoxyimino)ethyl>-3-methoxybenzoate

There total 7 articles about methyl 4-<2-<5--2-(N-methylamino)phenyl>-2-(acetoxyimino)ethyl>-3-methoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 108-24-7
acetic anhydride

: 110707-79-4
methyl 4-<2-<5--2-(N-methylamino)phenyl>-2-(hydroxyimino)ethyl>-3-methoxybenzoate

: 110707-77-2
methyl 4-<2-<5--2-(N-methylamino)phenyl>-2-(acetoxyimino)ethyl>-3-methoxybenzoate

Guidance literature:: With dmap; In dichloromethane; for 8h;
DOI:10.1021/jm00091a010

Reference yield:

: 1670-81-1,142396-03-0
1H-Indole-5-carboxylic acid

: 110707-77-2
methyl 4-<2-<5--2-(N-methylamino)phenyl>-2-(acetoxyimino)ethyl>-3-methoxybenzoate

Guidance literature:: Multi-step reaction with 6 steps

1: 80 percent / 4-(dimethylamino)pyridine, 1-<3-(dimethylamino)propyl>-3-ethylcarbodiimide hydrochloride / CH₂Cl₂ / 12 h

2: 1.) Ag₂O / 1.) dioxane, reflux, 1 h, 2.) dioxane, reflux, 3.5 h

3: 1.) NaH / 1.) DMF, from 0 deg C to 25 deg C, 35 min, 2.) DMF, 25 deg C, 1 h

4: 1.) ozone, 2.) Me₂S / 1.) CH₂Cl₂, MeOH, -78 deg C, 15 min, 2.) CH₂Cl₂, MeOH, from -78 deg C to RT

5: 66 percent / hydroxylamine hydrochloride, pyridine / 1.5 h / 120 °C

6: 79 percent / 4-(dimethylamino)pyridine / CH₂Cl₂ / 8 h

With pyridine; dmap; dimethylsulfide; hydroxylamine hydrochloride; sodium hydride; ozone; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; silver(l) oxide; In dichloromethane;
DOI:10.1021/jm00091a010

Reference yield:

: 6053-81-2
cyclopentylmethylamine

: 110707-77-2
methyl 4-<2-<5--2-(N-methylamino)phenyl>-2-(acetoxyimino)ethyl>-3-methoxybenzoate

Guidance literature:: Multi-step reaction with 6 steps

1: 80 percent / 4-(dimethylamino)pyridine, 1-<3-(dimethylamino)propyl>-3-ethylcarbodiimide hydrochloride / CH₂Cl₂ / 12 h

2: 1.) Ag₂O / 1.) dioxane, reflux, 1 h, 2.) dioxane, reflux, 3.5 h

3: 1.) NaH / 1.) DMF, from 0 deg C to 25 deg C, 35 min, 2.) DMF, 25 deg C, 1 h

4: 1.) ozone, 2.) Me₂S / 1.) CH₂Cl₂, MeOH, -78 deg C, 15 min, 2.) CH₂Cl₂, MeOH, from -78 deg C to RT

5: 66 percent / hydroxylamine hydrochloride, pyridine / 1.5 h / 120 °C

6: 79 percent / 4-(dimethylamino)pyridine / CH₂Cl₂ / 8 h

With pyridine; dmap; dimethylsulfide; hydroxylamine hydrochloride; sodium hydride; ozone; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; silver(l) oxide; In dichloromethane;
DOI:10.1021/jm00091a010