9-Benzyl-1,3-dimethyl-6-hydroxy-7-(3-methyl-2-butenyl)-pyrimido-[2,1-f]purine-2,4,8(1H,3H,9H)-trione

Base Information

• Chemical Name: 9-Benzyl-1,3-dimethyl-6-hydroxy-7-(3-methyl-2-butenyl)-pyrimido-[2,1-f]purine-2,4,8(1H,3H,9H)-trione
• CAS No.: 91297-71-1
• Molecular Formula: C₂₂H₂₃N₅O₄
• Molecular Weight: 421.456
• Mol file: 91297-71-1.mol

Synonyms:9-Benzyl-1,3-dimethyl-6-hydroxy-7-(3-methyl-2-butenyl)-pyrimido-[2,1-f]purine-2,4,8(1H,3H,9H)-trione

Chemical Property of 9-Benzyl-1,3-dimethyl-6-hydroxy-7-(3-methyl-2-butenyl)-pyrimido-[2,1-f]purine-2,4,8(1H,3H,9H)-trione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9-Benzyl-1,3-dimethyl-6-hydroxy-7-(3-methyl-2-butenyl)-pyrimido-[2,1-f]purine-2,4,8(1H,3H,9H)-trione

There total 2 articles about 9-Benzyl-1,3-dimethyl-6-hydroxy-7-(3-methyl-2-butenyl)-pyrimido-[2,1-f]purine-2,4,8(1H,3H,9H)-trione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

9-benzyl-1,3-dimethyl-6-(hydroxy)pyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-trione (91285-01-7) + prenyl bromide (870-63-3) → 9-Benzyl-1,3-dimethyl-6-hydroxy-7-(3-methyl-2-butenyl)-pyrimido-[2,1-f]purine-2,4,8(1H,3H,9H)-trione (91297-71-1) + 8-Benzyl-1,3-dimethyl-6,6-bis-(3-methyl-but-2-enyl)-1H,8H-1,3,4b,8,9-pentaaza-fluorene-2,4,5,7-tetraone (107569-03-9)

Guidance literature:

With sodium hydride; Yield given. Multistep reaction. Yields of byproduct given; 1.) DMF, 2.) DMF, 20 h;

Reference yield:

8-(benzylamino)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione (57000-13-2) → 9-Benzyl-1,3-dimethyl-6-hydroxy-7-(3-methyl-2-butenyl)-pyrimido-[2,1-f]purine-2,4,8(1H,3H,9H)-trione (91297-71-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 83 percent / 2.5 h / 200 °C

2: 1.) sodium hydride / 1.) DMF, 2.) DMF, 20

With sodium hydride;

Reference yield:

9-Benzyl-1,3-dimethyl-6-hydroxy-7-(3-methyl-2-butenyl)-pyrimido-[2,1-f]purine-2,4,8(1H,3H,9H)-trione (91297-71-1) → 9-Benzyl-1,3-dimethyl-6-hydroxy-7-prenyl-9H-8-oxopyrimido[2,1-f]purine-2,4-dione sodium salt (91285-57-3)

Guidance literature:

With sodium hydroxide;

upstream raw materials:

9-benzyl-1,3-dimethyl-6-(hydroxy)pyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-trione

prenyl bromide

8-(benzylamino)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione

Downstream raw materials:

9-Benzyl-1,3-dimethyl-6-hydroxy-7-prenyl-9H-8-oxopyrimido[2,1-f]purine-2,4-dione sodium salt