91285-01-7

Basic information

• Product Name: 9-benzyl-1,3-dimethyl-6-(hydroxy)pyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-trione
• Synonyms: 9-benzyl-1,3-dimethyl-6-(hydroxy)pyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-trione
• CAS NO: 91285-01-7
• Molecular Weight: 353.337
• Mol File: 91285-01-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 9-benzyl-1,3-dimethyl-6-(hydroxy)pyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-trione(CAS DataBase Reference)
• NIST Chemistry Reference: 9-benzyl-1,3-dimethyl-6-(hydroxy)pyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-trione(91285-01-7)
• EPA Substance Registry System: 9-benzyl-1,3-dimethyl-6-(hydroxy)pyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-trione(91285-01-7)

Safety Data

• Hazardous Substances Data: 91285-01-7(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 55552-69-7 2-ethylmalonyl dichloride 
• 57000-13-2 8-(benzylamino)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione 
• 105-53-3 diethyl malonate 

Downstream Products

• 102212-89-5 9-benzyl-1,3-dimethyl-6-hydroxy-7-nitrosopyrimido<2,1-f>purine-2,4,8-(1H,3H,9H)-trione 
• 91285-32-4 9-Benzyl-1,3-dimethyl-6-hydroxy-7-cyanomethyl-9H-8-oxopyrimido[2,1-f]purine-2,4-dione 
• 114748-09-3 9-benzyl-2,3-dihydro-1,3-dimethyl-6-(hydroxy)pyrimido[2,1-f]purine-4,8(1H,9H)-dione 
• 102212-64-6 9-benzyl-1,3-dimethyl-7-formyl-6-hydroxypyrimido<2,1-f>purine-2,48(1H,3H,9H)-trione sodium salt 
• 102212-60-2 7-acetamido-9-benzyl-1,3-dimethyl-6-hydroxypyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-trione 
• 102212-59-9 7-amino-9-benzyl-1,3-dimethyl-6-hydroxypyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-trione 
• 91285-49-3 1,3-Dimethyl-9-benzyl-6-methoxy-7-(n-propyl)-pyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-trione 
• 91284-86-5 9-Benzyl-1,3,7-trimethyl-6-hydroxy-9H-8-oxo-pyrimido[2,1-f]purine-2,4-dione 
• 91285-31-3 8-Benzyl-6-cyclohex-2-enyl-5-hydroxy-1,3-dimethyl-1H,8H-1,3,4b,8,9-pentaaza-fluorene-2,4,7-trione 
• 102212-90-8 9-benzyl-1,3-dimethyl-7-<(N,N-dimethylamino)methenyl>-6-hydroxypyrimido<2,1-f>purine-2,48(1H,3H,9H)-trione 
• 91285-33-5 9-benzyl-1,3-dimethyl-6-hydroxy-7-<(methoxycarbonyl)methyl>pyrimido<2,1-f>purine-2,4,8(1H,3H,9H)-trione 
• 107569-04-0 (8-Benzyl-6-methoxycarbonylmethyl-1,3-dimethyl-2,4,5,7-tetraoxo-1,2,3,4,5,6,7,8-octahydro-1,3,4b,8,9-pentaaza-fluoren-6-yl)-acetic acid methyl ester 
• 91284-85-4 9-Benzyl-1,3-dimethyl-6-hydroxy-7-(n-propyl)-pyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-trione 
• 102212-70-4 8-Benzyl-6-((E)-but-2-enyl)-5-hydroxy-1,3-dimethyl-1H,8H-1,3,4b,8,9-pentaaza-fluorene-2,4,7-trione 

Relevant articles and documents

Method of treating hyperploliferative skin disease with substituted-2,3-dihydro-6-substituted -pyrimido[2,1]-purine-4,8(1H,9H)diones

Substituted 2,3-dihydro-6-substituted-pyrimido[2,1-f]purine-4,8(1H,9H)-diones, their tautomers and salts, are disclosed for use as antihyperproliferative skin disease agents. Methods for their preparation and use are described.

Anti-inflammatory substituted 9H-8-oxo-pyrimido[2,1-f]purine-2,4-diones

Substituted 9H-8-oxo-pyrimido[2,1-f]purine-2,4-diones their tautomers and salts are anti-inflammatory agents. Methods for their preparation and use are described.

REGIOSPECIFIC ALKYLATION OF 9-BENZYL-1,3-DIMETHYL-6-HYDROXYPYRIMIDOPURINE-2,4,8(1H,3H,9H)-TRIONE

The sodium salt of 9-benzyl-1,3-dimethyl-6-hydroxypyrimidopurine-2,4,8(1H,3H,9H)-trione (1a) reacted with a series of alkyl halides in N,N-dimethylformamide to yield 7-carbon alkylated products (1b-1).No O-alkylated products were detected.Isolated