Technology Process of (4R)-4-(4-methoxybenzyloxy)hex-5-enoic acid
There total 7 articles about (4R)-4-(4-methoxybenzyloxy)hex-5-enoic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium chlorite; sodium dihydrogen phosphate monohydrate;
In
water; dimethyl sulfoxide;
at 20 ℃;
Inert atmosphere;
DOI:10.1039/b916198h
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / tetrahydrofuran; dimethyl sulfoxide / 3 h / 20 °C
2: sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene; sodium perchlorate / water; tert-butyl alcohol / 2 h / 0 - 20 °C
With
sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene; sodium perchlorate; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione;
In
tetrahydrofuran; water; dimethyl sulfoxide; tert-butyl alcohol;
DOI:10.1055/s-0029-1217556
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1H-imidazole; iodine; triphenylphosphine / tetrahydrofuran / 0.25 h / 0 °C
2: sodium iodide; zinc / methanol / 4 h / Reflux
3: sodium hydride / tetrahydrofuran / 4 h / 0 - 20 °C
4: tetrabutyl ammonium fluoride / tetrahydrofuran / 7 h / 0 - 20 °C
5: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / tetrahydrofuran; dimethyl sulfoxide / 3 h / 20 °C
6: sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene; sodium perchlorate / water; tert-butyl alcohol / 2 h / 0 - 20 °C
With
1H-imidazole; sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene; sodium perchlorate; tetrabutyl ammonium fluoride; iodine; sodium hydride; triphenylphosphine; sodium iodide; zinc; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione;
In
tetrahydrofuran; methanol; water; dimethyl sulfoxide; tert-butyl alcohol;
DOI:10.1055/s-0029-1217556