Technology Process of N-benzyl-5-phenyl-1,3,4,5-tetrahydro-1,2,5,6,8-pentaazaacenaphthylen-7-amine
There total 6 articles about N-benzyl-5-phenyl-1,3,4,5-tetrahydro-1,2,5,6,8-pentaazaacenaphthylen-7-amine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
7-(methylthio)-5-phenyl-1,3,4,5-tetrahydro-1,2,5,6,8-pentaazaacenaphthylene;
With
3-chloro-benzenecarboperoxoic acid;
In
dichloromethane;
at 20 ℃;
for 4h;
benzylamine;
In
dimethyl sulfoxide;
at 100 ℃;
for 10h;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 7 h / 100 °C
2.1: lithium diisopropyl amide / tetrahydrofuran / Cooling with ice
3.1: hydrazine hydrate; triethylamine / 1,4-dioxane / 5 - 6 h / 20 °C
4.1: water; sodium hydroxide / ethanol / 3 h / 60 °C
5.1: hydrogenchloride / 1,4-dioxane / 16 h / Reflux
6.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 4 h / 20 °C
6.2: 10 h / 100 °C
With
hydrogenchloride; water; hydrazine hydrate; triethylamine; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid; sodium hydroxide; lithium diisopropyl amide;
In
tetrahydrofuran; 1,4-dioxane; ethanol; dichloromethane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: hydrogenchloride / 1,4-dioxane / 16 h / Reflux
2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 4 h / 20 °C
2.2: 10 h / 100 °C
With
hydrogenchloride; 3-chloro-benzenecarboperoxoic acid;
In
1,4-dioxane; dichloromethane;
