1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ⁴-penicillanic acid cyanomethyl ester

Base Information

• Chemical Name: 1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ⁴-penicillanic acid cyanomethyl ester
• CAS No.: 99673-35-5
• Molecular Formula: C₁₈H₁₉N₃O₅S
• Molecular Weight: 389.432
• Mol file: 99673-35-5.mol

Synonyms:1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ⁴-penicillanic acid cyanomethyl ester

Chemical Property of 1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ⁴-penicillanic acid cyanomethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ⁴-penicillanic acid cyanomethyl ester

There total 1 articles about 1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ⁴-penicillanic acid cyanomethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloroacetonitrile (107-14-2) + 1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ4-penicillanic acid; potassium salt (39906-59-7) → 1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ4-penicillanic acid cyanomethyl ester (99673-35-5)

Guidance literature:

Multistep reaction; (i) KI, (ii) H₂O₂, AcOH;

DOI:10.1016/S0040-4039(00)70886-0

Reference yield:

1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ4-penicillanic acid cyanomethyl ester (99673-35-5) → Penicillin G 1-(s)-oxide (4052-54-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In water;

DOI:10.1016/S0040-4039(00)70886-0

upstream raw materials:

chloroacetonitrile

1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ⁴-penicillanic acid; potassium salt

Downstream raw materials:

Penicillin G 1-(s)-oxide