1-(biphenyl-2-ylacetyl)-4-[(6-fluoro-2-naphthyl)methyl]piperazine hydrochloride

Base Information

• Chemical Name: 1-(biphenyl-2-ylacetyl)-4-[(6-fluoro-2-naphthyl)methyl]piperazine hydrochloride
• CAS No.: 1189141-83-0
• Molecular Formula: C₂₉H₂₇FN₂O*ClH
• Molecular Weight: 475.006

Synonyms:1-(biphenyl-2-ylacetyl)-4-[(6-fluoro-2-naphthyl)methyl]piperazine hydrochloride

Chemical Property of 1-(biphenyl-2-ylacetyl)-4-[(6-fluoro-2-naphthyl)methyl]piperazine hydrochloride

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Technology Process of 1-(biphenyl-2-ylacetyl)-4-[(6-fluoro-2-naphthyl)methyl]piperazine hydrochloride

There total 1 articles about 1-(biphenyl-2-ylacetyl)-4-[(6-fluoro-2-naphthyl)methyl]piperazine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

biphenylacetic acid (14676-52-9) + 1-[(6-fluoro-2-naphthyl)methyl]piperazine dihydrochloride → 1-(biphenyl-2-ylacetyl)-4-[(6-fluoro-2-naphthyl)methyl]piperazine hydrochloride (1189141-83-0)

Guidance literature:

biphenylacetic acid; 1-[(6-fluoro-2-naphthyl)methyl]piperazine dihydrochloride; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃;

With hydrogenchloride; In ethyl acetate;

DOI:10.1016/j.bmc.2009.06.066

upstream raw materials:

biphenylacetic acid

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