C₁₃H₁₆O₃

Base Information

• Chemical Name: C₁₃H₁₆O₃
• CAS No.: 1588818-29-4
• Molecular Formula: C₁₃H₁₆O₃
• Molecular Weight: 220.268
• Mol file: 1588818-29-4.mol

Synonyms:C₁₃H₁₆O₃

Chemical Property of C₁₃H₁₆O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₃H₁₆O₃

There total 8 articles about C₁₃H₁₆O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(4-methyl-3-penten-1-yl)benzoic acid (1588818-26-1) → C13H16O3 (1588818-29-4)

Guidance literature:

With peracetic acid; sodium carbonate; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1080/10286020.2013.879121

Reference yield:

2-(2-carboxyethyl)benzoic acid (776-79-4) → C13H16O3 (1588818-29-4)

Guidance literature:

Multi-step reaction with 7 steps

1.1: sulfuric acid / 2 h / 20 °C

2.1: lithium borohydride / 1,4-dioxane / 6.5 h / 100 °C / Inert atmosphere

3.1: sulfuric acid / 36 h / Reflux

4.1: pyridinium chlorochromate; silica gel / dichloromethane / 20 °C

5.1: n-butyllithium / diethyl ether / 1 h / -10 - 20 °C / Inert atmosphere

5.2: 3 h / 20 °C / Inert atmosphere

6.1: sodium hydroxide / methanol; water / 12 h / Reflux

6.2: pH 1 - 2

7.1: peracetic acid; sodium carbonate / dichloromethane / 2 h / 20 °C

With peracetic acid; lithium borohydride; n-butyllithium; sulfuric acid; silica gel; sodium carbonate; pyridinium chlorochromate; sodium hydroxide; In 1,4-dioxane; methanol; diethyl ether; dichloromethane; water; 5.1: |Wittig Olefination;

DOI:10.1080/10286020.2013.879121

Reference yield:

(E)-o-carboxycinnamic acid (18454-53-0) → C13H16O3 (1588818-29-4)

Guidance literature:

Multi-step reaction with 8 steps

1.1: palladium dichloride; sodium hydroxide; formic acid / 24 h / 65 °C

2.1: sulfuric acid / 2 h / 20 °C

3.1: lithium borohydride / 1,4-dioxane / 6.5 h / 100 °C / Inert atmosphere

4.1: sulfuric acid / 36 h / Reflux

5.1: pyridinium chlorochromate; silica gel / dichloromethane / 20 °C

6.1: n-butyllithium / diethyl ether / 1 h / -10 - 20 °C / Inert atmosphere

6.2: 3 h / 20 °C / Inert atmosphere

7.1: sodium hydroxide / methanol; water / 12 h / Reflux

7.2: pH 1 - 2

8.1: peracetic acid; sodium carbonate / dichloromethane / 2 h / 20 °C

With peracetic acid; lithium borohydride; n-butyllithium; formic acid; sulfuric acid; silica gel; sodium carbonate; pyridinium chlorochromate; sodium hydroxide; palladium dichloride; In 1,4-dioxane; methanol; diethyl ether; dichloromethane; water; 6.1: |Wittig Olefination;

DOI:10.1080/10286020.2013.879121

upstream raw materials:

(E)-o-carboxycinnamic acid

2-(2-carboxyethyl)benzoic acid

2-(2-methoxycarbonylethyl)benzoic acid

2-(3-hydroxypropane)benzoic acid