Technology Process of tert-butyl-((2S,4R)-2,4-dimethylhex-5-enyloxy)diphenylsilane
There total 4 articles about tert-butyl-((2S,4R)-2,4-dimethylhex-5-enyloxy)diphenylsilane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Methyltriphenylphosphonium bromide;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at 0 ℃;
for 0.5h;
Inert atmosphere;
(2R,4S)-5-{[tert-butyl(diphenyl)silyl]oxy}-2,4-dimethylpentanal;
In
tetrahydrofuran; hexane;
at 0 - 23 ℃;
for 1h;
Inert atmosphere;
DOI:10.1021/ol101801u
- Guidance literature:
-
Multi-step reaction with 3 steps
1: LAB / tetrahydrofuran / Inert atmosphere
2: tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide / dichloromethane / Inert atmosphere
3: n-butyllithium / tetrahydrofuran / Inert atmosphere
With
n-butyllithium; tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide;
In
tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmc.2011.01.027
- Guidance literature:
-
Multi-step reaction with 4 steps
1: lithium chloride; lithium diisopropyl amide / tetrahydrofuran / Inert atmosphere
2: LAB / tetrahydrofuran / Inert atmosphere
3: tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide / dichloromethane / Inert atmosphere
4: n-butyllithium / tetrahydrofuran / Inert atmosphere
With
n-butyllithium; tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide; lithium chloride; lithium diisopropyl amide;
In
tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmc.2011.01.027
