ethyl 2,4-di-O-benzoyl-3-O-(3-O-benzyl-4-O-chloroacetyl-2-O-methyl-α-L-fucopyranosyl)-1-thio-α-L-rhamnopyranoside

Base Information

Chemical Name:ethyl 2,4-di-O-benzoyl-3-O-(3-O-benzyl-4-O-chloroacetyl-2-O-methyl-α-L-fucopyranosyl)-1-thio-α-L-rhamnopyranoside
CAS No.:148404-63-1
Molecular Formula:C₃₈H₄₃ClO₁₁S
Molecular Weight:743.272
Hs Code.:

Synonyms:ethyl 2,4-di-O-benzoyl-3-O-(3-O-benzyl-4-O-chloroacetyl-2-O-methyl-α-L-fucopyranosyl)-1-thio-α-L-rhamnopyranoside

Suppliers and Price of ethyl 2,4-di-O-benzoyl-3-O-(3-O-benzyl-4-O-chloroacetyl-2-O-methyl-α-L-fucopyranosyl)-1-thio-α-L-rhamnopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 2,4-di-O-benzoyl-3-O-(3-O-benzyl-4-O-chloroacetyl-2-O-methyl-α-L-fucopyranosyl)-1-thio-α-L-rhamnopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 2,4-di-O-benzoyl-3-O-(3-O-benzyl-4-O-chloroacetyl-2-O-methyl-α-L-fucopyranosyl)-1-thio-α-L-rhamnopyranoside

There total 6 articles about ethyl 2,4-di-O-benzoyl-3-O-(3-O-benzyl-4-O-chloroacetyl-2-O-methyl-α-L-fucopyranosyl)-1-thio-α-L-rhamnopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 135303-37-6
ethyl 2,4-di-O-benzoyl-1-thio-α-L-rhamnopyranoside

: 143570-50-7
ethyl 3-O-benzyl-4-O-chloroacetyl-2-O-methyl-1-thio-β-L-fucopyranoside

: 148404-63-1
ethyl 2,4-di-O-benzoyl-3-O-(3-O-benzyl-4-O-chloroacetyl-2-O-methyl-α-L-fucopyranosyl)-1-thio-α-L-rhamnopyranoside

Guidance literature:: With iodonium(di-γ-collidine) perchlorate; 4 A molecular sieve; In diethyl ether; 1,2-dichloro-ethane; at 20 ℃; for 0.25h;
DOI:10.1016/0008-6215(93)80102-K

Reference yield:

: 100-39-0
benzyl bromide

: 148404-63-1
ethyl 2,4-di-O-benzoyl-3-O-(3-O-benzyl-4-O-chloroacetyl-2-O-methyl-α-L-fucopyranosyl)-1-thio-α-L-rhamnopyranoside

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) dibutyltin oxide, 2.) CsF / 1.) MeOH, reflux, 4 h, 2.) DMF, 20 deg C, 16 h

2: 92 percent / NaHCO₃ / dimethylformamide / 17 h / 20 °C

3: 61 percent / iodonium di-sym-collidine perchlorate, 4 Angstroem molecular sieves / 1,2-dichloro-ethane; diethyl ether / 0.25 h / 20 °C

With iodonium(di-γ-collidine) perchlorate; 4 A molecular sieve; di(n-butyl)tin oxide; sodium hydrogencarbonate; cesium fluoride; In diethyl ether; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
DOI:10.1016/0008-6215(93)80102-K

Reference yield:

: 146399-61-3
ethyl 2-O-methyl-1-thio-β-L-fucopyranoside

: 148404-63-1
ethyl 2,4-di-O-benzoyl-3-O-(3-O-benzyl-4-O-chloroacetyl-2-O-methyl-α-L-fucopyranosyl)-1-thio-α-L-rhamnopyranoside

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) dibutyltin oxide, 2.) CsF / 1.) MeOH, reflux, 4 h, 2.) DMF, 20 deg C, 16 h

2: 92 percent / NaHCO₃ / dimethylformamide / 17 h / 20 °C

3: 61 percent / iodonium di-sym-collidine perchlorate, 4 Angstroem molecular sieves / 1,2-dichloro-ethane; diethyl ether / 0.25 h / 20 °C

With iodonium(di-γ-collidine) perchlorate; 4 A molecular sieve; di(n-butyl)tin oxide; sodium hydrogencarbonate; cesium fluoride; In diethyl ether; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
DOI:10.1016/0008-6215(93)80102-K