11β-(2,4-dimethoxyphenyl)-3,3-<2,2-dimethyl-1,3-propanediylbis(oxy)>-5α-estr-9-ene-5,17β-diol

Base Information

Chemical Name:11β-(2,4-dimethoxyphenyl)-3,3-<2,2-dimethyl-1,3-propanediylbis(oxy)>-5α-estr-9-ene-5,17β-diol
CAS No.:149835-49-4
Molecular Formula:C₃₁H₄₄O₆
Molecular Weight:512.687
Hs Code.:

Synonyms:11β-(2,4-dimethoxyphenyl)-3,3-<2,2-dimethyl-1,3-propanediylbis(oxy)>-5α-estr-9-ene-5,17β-diol

Suppliers and Price of 11β-(2,4-dimethoxyphenyl)-3,3-<2,2-dimethyl-1,3-propanediylbis(oxy)>-5α-estr-9-ene-5,17β-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 11β-(2,4-dimethoxyphenyl)-3,3-<2,2-dimethyl-1,3-propanediylbis(oxy)>-5α-estr-9-ene-5,17β-diol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 11β-(2,4-dimethoxyphenyl)-3,3-<2,2-dimethyl-1,3-propanediylbis(oxy)>-5α-estr-9-ene-5,17β-diol

There total 1 articles about 11β-(2,4-dimethoxyphenyl)-3,3-<2,2-dimethyl-1,3-propanediylbis(oxy)>-5α-estr-9-ene-5,17β-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 138109-49-6
2,4-dimethoxyphenylmagnesium bromide

: 104068-77-1
3,3-[2,2-dimethyl-1,3-propanediylbis(oxy)]-5α,10α-epoxy-estr-9(11)-en-17β-ol

: 149835-49-4
11β-(2,4-dimethoxyphenyl)-3,3-<2,2-dimethyl-1,3-propanediylbis(oxy)>-5α-estr-9-ene-5,17β-diol

Guidance literature:: With copper(l) chloride; Yield given. Multistep reaction; 1) THF, 5 deg C, 2) THF, 5 deg C to RT, overnight;
DOI:10.1016/S0040-4020(01)80365-3

Reference yield: 58.0%

: 149835-49-4
11β-(2,4-dimethoxyphenyl)-3,3-<2,2-dimethyl-1,3-propanediylbis(oxy)>-5α-estr-9-ene-5,17β-diol

: 11β-(2,4-dimethoxyphenyl)-17β-hydroxyestra-5(10),9(11)-dien-3-one

: 149835-51-8
11β-(2,4-dimethoxyphenyl)-17β-hydroxyestra-4,9-dien-3-one

: 11-(2,4-dimethoxyphenyl)-3,3-<2,2-dimethyl-1,3-propanediylbis(oxy)>estra-5(10),9(11)-dien-17β-ol

Guidance literature:: With pyridinium p-toluenesulfonate; In ethanol; water; for 0.75h;
DOI:10.1016/S0040-4020(01)80365-3

Reference yield:

: 149835-49-4
11β-(2,4-dimethoxyphenyl)-3,3-<2,2-dimethyl-1,3-propanediylbis(oxy)>-5α-estr-9-ene-5,17β-diol

: 149279-78-7
11β-(2,4-dimethoxyphenyl)-17β-hydroxyestr-5(10)-en-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: 58 percent / pyridinium p-toluenesulfonate / ethanol; H₂O / 0.75 h / 0 °C

2: 68 percent / Li/NH₃(l) / 2-methyl-propan-2-ol; tetrahydrofuran / 1 h / -78 °C

With ammonia; pyridinium p-toluenesulfonate; lithium; In tetrahydrofuran; ethanol; water; tert-butyl alcohol;
DOI:10.1016/S0040-4020(01)80365-3