6-[(1S,2R,4S)-4-Benzyloxymethyl-2-(2-methoxy-ethoxymethoxy)-cyclohexanecarbonyl]-2,3-dihydro-pyran-4-one

Base Information

Chemical Name:6-[(1S,2R,4S)-4-Benzyloxymethyl-2-(2-methoxy-ethoxymethoxy)-cyclohexanecarbonyl]-2,3-dihydro-pyran-4-one
CAS No.:106569-71-5
Molecular Formula:C₂₄H₃₂O₇
Molecular Weight:432.514
Hs Code.:

Synonyms:6-[(1S,2R,4S)-4-Benzyloxymethyl-2-(2-methoxy-ethoxymethoxy)-cyclohexanecarbonyl]-2,3-dihydro-pyran-4-one

Suppliers and Price of 6-[(1S,2R,4S)-4-Benzyloxymethyl-2-(2-methoxy-ethoxymethoxy)-cyclohexanecarbonyl]-2,3-dihydro-pyran-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6-[(1S,2R,4S)-4-Benzyloxymethyl-2-(2-methoxy-ethoxymethoxy)-cyclohexanecarbonyl]-2,3-dihydro-pyran-4-one

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-[(1S,2R,4S)-4-Benzyloxymethyl-2-(2-methoxy-ethoxymethoxy)-cyclohexanecarbonyl]-2,3-dihydro-pyran-4-one

There total 19 articles about 6-[(1S,2R,4S)-4-Benzyloxymethyl-2-(2-methoxy-ethoxymethoxy)-cyclohexanecarbonyl]-2,3-dihydro-pyran-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 131067-65-7,131067-66-8
6-{[(1R,2R,4S)-4-Benzyloxymethyl-2-(2-methoxy-ethoxymethoxy)-cyclohexyl]-hydroxy-methyl}-2,3-dihydro-pyran-4-one

: 106569-71-5
6-[(1S,2R,4S)-4-Benzyloxymethyl-2-(2-methoxy-ethoxymethoxy)-cyclohexanecarbonyl]-2,3-dihydro-pyran-4-one

Guidance literature:: With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane; at -78 ℃; for 0.5h; Yield given;

Reference yield:

: 76469-08-4
5-octynolic acid

: 106569-71-5
6-[(1S,2R,4S)-4-Benzyloxymethyl-2-(2-methoxy-ethoxymethoxy)-cyclohexanecarbonyl]-2,3-dihydro-pyran-4-one

Guidance literature:: Multi-step reaction with 13 steps

1: (COCl)2

2: 1) nBuLi / 1) THF

3: 1) (Me₂Si)2NLi / 1) THF, -78 deg C, 2) THF, -78 to 0 deg C

4: LiAlH₄ / tetrahydrofuran

5: KH / tetrahydrofuran

6: 1) ozone

7: 98 percent / hydrogen, quinoline / 5percent Pd/CaCO₃ / hexane

8: Me₂AlCl / CH₂Cl₂

10: ozone

11: 1) t-BuLi / 1) THF, 2) THF, HMPA

12: H₃O⁽¹⁺⁾

13: 1) DMSO, (COCl)2, 2) Et₃N / 1) -78 deg C, 2) -78 to -10 deg C

With quinoline; lithium aluminium tetrahydride; n-butyllithium; oxalyl dichloride; (Me₂Si)2NLi; oxonium; hydrogen; tert.-butyl lithium; dimethylaluminum chloride; potassium hydride; ozone; dimethyl sulfoxide; triethylamine; Lindlar's catalyst; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/ja00238a060

Reference yield:

: 100-39-0
benzyl bromide

: 106569-71-5
6-[(1S,2R,4S)-4-Benzyloxymethyl-2-(2-methoxy-ethoxymethoxy)-cyclohexanecarbonyl]-2,3-dihydro-pyran-4-one

Guidance literature:: Multi-step reaction with 9 steps

1: KH / tetrahydrofuran

2: 1) ozone

3: 98 percent / hydrogen, quinoline / 5percent Pd/CaCO₃ / hexane

4: Me₂AlCl / CH₂Cl₂

6: ozone

7: 1) t-BuLi / 1) THF, 2) THF, HMPA

8: H₃O⁽¹⁺⁾

9: 1) DMSO, (COCl)2, 2) Et₃N / 1) -78 deg C, 2) -78 to -10 deg C

With quinoline; oxalyl dichloride; oxonium; hydrogen; tert.-butyl lithium; dimethylaluminum chloride; potassium hydride; ozone; dimethyl sulfoxide; triethylamine; Lindlar's catalyst; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/ja00238a060