Technology Process of L-ribo-Hexonic acid, 3-(benzoylamino)-2,3,6-trideoxy-, gamma-lactone
There total 24 articles about L-ribo-Hexonic acid, 3-(benzoylamino)-2,3,6-trideoxy-, gamma-lactone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 100 percent / imidazole / dimethylformamide / 1.5 h / Ambient temperature
2: 97 percent / H2 / 5percent Pd on CaCO3 poisoned with lead / methanol / 0.17 h / 760 Torr / Ambient temperature
3: 94 percent / tert-BuOK / tetrahydrofuran / 0.33 h / 0 °C
4: 1.) 1N aq. NaOH, 2.) NaHCO3 / 1.) EtOH, 60 deg C, 12 h, 2.) EtOH, acetone, RT, 2 h
With
1H-imidazole; sodium hydroxide; potassium tert-butylate; hydrogen; sodium hydrogencarbonate;
Lindlar catalyst;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1021/jo00391a032
