C₂₄H₃₆O₂Si

Base Information

• Chemical Name: C₂₄H₃₆O₂Si
• CAS No.: 1310330-40-5
• Molecular Formula: C₂₄H₃₆O₂Si
• Molecular Weight: 384.634
• Mol file: 1310330-40-5.mol

Synonyms:C₂₄H₃₆O₂Si

Chemical Property of C₂₄H₃₆O₂Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₃₆O₂Si

There total 4 articles about C₂₄H₃₆O₂Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

non-8-enoic acid (31642-67-8) + (E)-4-(benzyldimethylsilyl)hexa-3,5-dien-1-ol (1310330-33-6) → C24H36O2Si (1310330-40-5)

Guidance literature:

With 4-pyrrolidin-1-ylpyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; for 1h; Inert atmosphere;

DOI:10.1021/ja2031085

Reference yield:

(Z)-4-(benzyldimethylsilyl)-4-iodobut-3-en-1-ol → C24H36O2Si (1310330-40-5)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloro bis(acetonitrile) palladium(II); Tetrabutylammoniumsalz der Diphenylphosphinsaeure / N,N-dimethyl-formamide / 1 h / Inert atmosphere

2: 4-pyrrolidin-1-ylpyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 1 h / Inert atmosphere

With dichloro bis(acetonitrile) palladium(II); 4-pyrrolidin-1-ylpyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; Tetrabutylammoniumsalz der Diphenylphosphinsaeure; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ja2031085

Reference yield:

4-benzyldimethylsilyl-1-(2-tetrahydropyranyloxy)-3-butyne (460752-17-4) → C24H36O2Si (1310330-40-5)

Guidance literature:

Multi-step reaction with 4 steps

1.1: methanol; toluene-4-sulfonic acid / 2 h / Inert atmosphere

2.1: triethylaluminum / dichloromethane; toluene / 0 - 20 °C / Inert atmosphere

2.2: 58 h / 20 °C / Inert atmosphere

2.3: 1 h / -78 - 0 °C / Inert atmosphere

3.1: dichloro bis(acetonitrile) palladium(II); Tetrabutylammoniumsalz der Diphenylphosphinsaeure / N,N-dimethyl-formamide / 1 h / Inert atmosphere

4.1: 4-pyrrolidin-1-ylpyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 1 h / Inert atmosphere

With methanol; dichloro bis(acetonitrile) palladium(II); triethylaluminum; 4-pyrrolidin-1-ylpyridine; toluene-4-sulfonic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; Tetrabutylammoniumsalz der Diphenylphosphinsaeure; In dichloromethane; N,N-dimethyl-formamide; toluene;

DOI:10.1021/ja2031085

upstream raw materials:

4-benzyldimethylsilyl-1-(2-tetrahydropyranyloxy)-3-butyne

non-8-enoic acid

(E)-4-(benzyldimethylsilyl)hexa-3,5-dien-1-ol

4-(benzyldimethyl-silyl)but-3-yn-1-ol

Downstream raw materials:

C₂₂H₃₂O₂Si