digitoxigenin arabinoside

Base Information

• Chemical Name: digitoxigenin arabinoside
• CAS No.: 78614-49-0
• Molecular Formula: C₂₈H₄₂O₈
• Molecular Weight: 506.637
• Mol file: 78614-49-0.mol

Synonyms:digitoxigenin arabinoside

Chemical Property of digitoxigenin arabinoside

Chemical Property:

• Vapor Pressure: 2.92E-23mmHg at 25°C
• Boiling Point: 709.5°C at 760 mmHg
• Flash Point: 233.6°C
• PSA: 125.68000
• Density: 1.33g/cm³
• LogP: 2.06760

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of digitoxigenin arabinoside

There total 6 articles about digitoxigenin arabinoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-O-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)digitoxigenin (99617-50-2) → 3-O-β-D-ribofuranosyldigitoxigenin (78614-49-0,99604-84-9,105761-94-2,119323-62-5)

Guidance literature:

Reference yield:

Digitoxigenin-3β-O-α-L-arabinofuranosidtribenzoat (78614-48-9) → Digitoxigenin-3β-O-α-L-arabinofuranosid (78614-49-0,99604-84-9,105761-94-2,119323-62-5)

Guidance literature:

With ammonia; In methanol; at 3 - 7 ℃; for 48h; Yield given;

Reference yield:

2,3,5-tri-O-acetyl-D-ribofuranosyl bromide (39110-68-4) → 3-O-β-D-ribofuranosyldigitoxigenin (78614-49-0,99604-84-9,105761-94-2,119323-62-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 83 percent / mercuric cyanide / acetonitrile / 2 h / 60 °C

2: 61 percent / ammonia / methanol / 18 h / Ambient temperature

With ammonia; mercury(II) cyanide; In methanol; acetonitrile;

DOI:10.1021/jm00152a012

upstream raw materials:

Digitoxigenin-3β-O-α-L-arabinofuranosidtribenzoat

2,3,5-tri-O-benzoyl-α-L-arabinofuranosyl chloride

(+)-digitoxigenin

3-O-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)digitoxigenin

Downstream raw materials:

3-O-<5-O-(p-tolylsulfonyl)-β-D-ribofuranosyl>digitoxigenin

L-arabinose

(+)-digitoxigenin

Refernces

• 1、 Schwabe,Tschiersch. "Synthesis and properties of digitoxigenin-3β-O-α-L-arabinofuranoside". . p. 827 - 828. Retrieved 2007/10/02.