(2-bromo-5-chlorophenyl)methanediyl diacetate

Base Information

• Chemical Name: (2-bromo-5-chlorophenyl)methanediyl diacetate
• CAS No.: 882772-93-2
• Molecular Formula: C₁₁H₁₀BrClO₄
• Molecular Weight: 321.555
• Mol file: 882772-93-2.mol

Synonyms:(2-bromo-5-chlorophenyl)methanediyl diacetate

Chemical Property of (2-bromo-5-chlorophenyl)methanediyl diacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-bromo-5-chlorophenyl)methanediyl diacetate

There total 1 articles about (2-bromo-5-chlorophenyl)methanediyl diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-5-chlorotoluene (14495-51-3) + acetic anhydride (108-24-7) → (2-bromo-5-chlorophenyl)methanediyl diacetate (882772-93-2)

Guidance literature:

With chromium(VI) oxide; sulfuric acid; acetic acid; at 0 ℃; for 3.5h;

DOI:10.1021/jf800273t

Reference yield: 83.0%

(2-bromo-5-chlorophenyl)methanediyl diacetate (882772-93-2) → 2-bromo-5-chlorobenzaldehyde (174265-12-4)

Guidance literature:

With sulfuric acid; In methanol; water; for 0.5h; Reflux;

DOI:10.2298/JSC150116013B

Reference yield:

(2-bromo-5-chlorophenyl)methanediyl diacetate (882772-93-2) → 3-[(Z)-2-(2-bromo-5-chlorophenyl)ethenyl]-4-chloropyridine

Guidance literature:

Multi-step reaction with 2 steps

1.1: sulfuric acid / methanol; water / 0.5 h / Reflux

2.1: potassium tert-butylate / tetrahydrofuran / 0.5 h

2.2: 16 h / 20 °C

With sulfuric acid; potassium tert-butylate; In tetrahydrofuran; methanol; water; 2.2: |Wittig Olefination;

DOI:10.2298/JSC150116013B

upstream raw materials:

2-bromo-5-chlorotoluene

acetic anhydride

Downstream raw materials:

2-bromo-5-chlorobenzaldehyde

Refernces

• 1、 Tu, Song,Xu, Long-He,Ye, Li-Yi,Wang, Xi,Sha, Yong,Xiao, Zong-Yuan. "Synthesis and fungicidal activities of novel indene-substituted oxime ether strobilurins". experimental part. p. 5247 - 5253. Retrieved 2010/04/06.