4'-Chlorodiazepam

Base Information Edit

Chemical Name:4'-Chlorodiazepam
CAS No.:14439-61-3
Molecular Formula:C16H12 Cl2 N2 O
Molecular Weight:319.19
Hs Code.:2933990090
European Community (EC) Number:634-296-3
UNII:2QW0IK1742
DSSTox Substance ID:DTXSID3041116
Nikkaji Number:J23.706J
Wikipedia:Ro5-4864
Wikidata:Q7339205
Pharos Ligand ID:2KB2PGDYW7WK
ChEMBL ID:CHEMBL286346
Mol file:14439-61-3.mol

Synonyms:4'-chlorodiazepam;chlordiazepam;Ro 5-4864;Ro-05-4864;Ro5-4864

Suppliers and Price of 4'-Chlorodiazepam

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
4′-Chlorodiazepam ≥98% (TLC)
5mg
$ 285.00

Sigma-Aldrich
TSPO Agonist, Ro5-4864 - CAS 14439-61-3 - Calbiochem
10 mg
$ 200.00

Sigma-Aldrich
TSPO Agonist, Ro5-4864 - CAS 14439-61-3 - CalbiochemA 4'-chloro derivative of diazepam that lacks affinity for GABA-A receptors, but can serve as a ligand for the peripheral benzodiazepine receptor.
5085780001
$ 193.00

Crysdot
Ro5-4864 97%
25mg
$ 315.00

American Custom Chemicals Corporation
RO-54864 95.00%
100MG
$ 663.74

Total 25 raw suppliers

Chemical Property of 4'-Chlorodiazepam Edit

Chemical Property:

Vapor Pressure:8.43E-11mmHg at 25°C
Melting Point:160-163 °C
Boiling Point:517.1°Cat760mmHg
PKA:3.08±0.10(Predicted)
Flash Point:266.6°C
PSA：32.67000
Density:1.35g/cm³
LogP:3.30780
Storage Temp.:+2C to +8C
Solubility.:ethanol: 17 mg/mL
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:318.0326684
Heavy Atom Count:21
Complexity:432

Purity/Quality:

98%,99%, ^*data from raw suppliers

4′-Chlorodiazepam ≥98% (TLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22
Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=C(C=C3)Cl
Uses 4′-Chlorodiazepam has been used as a translocator protein ligand in mitochondrial functional studies. It has also been used to investigate its protective effects on glucose deprived T98G astrocyte cell lines.

Technology Process of 4'-Chlorodiazepam

There total 8 articles about 4'-Chlorodiazepam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%