methyl 4-[(6-chloro-4-methoxy-3-methyl-2-{[4-(trifluoromethoxy)phenyl]-imino}-2,3-dihydro-1H-benzimidazol-1-yl)methyl]-N-1H-tetrazol-5-ylbenzoate

Base Information

Chemical Name:methyl 4-[(6-chloro-4-methoxy-3-methyl-2-{[4-(trifluoromethoxy)phenyl]-imino}-2,3-dihydro-1H-benzimidazol-1-yl)methyl]-N-1H-tetrazol-5-ylbenzoate
CAS No.:859877-53-5
Molecular Formula:C₂₅H₂₁ClF₃N₃O₄
Molecular Weight:519.908
Hs Code.:

Synonyms:methyl 4-[(6-chloro-4-methoxy-3-methyl-2-{[4-(trifluoromethoxy)phenyl]-imino}-2,3-dihydro-1H-benzimidazol-1-yl)methyl]-N-1H-tetrazol-5-ylbenzoate

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Chemical Property of methyl 4-[(6-chloro-4-methoxy-3-methyl-2-{[4-(trifluoromethoxy)phenyl]-imino}-2,3-dihydro-1H-benzimidazol-1-yl)methyl]-N-1H-tetrazol-5-ylbenzoate

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Technology Process of methyl 4-[(6-chloro-4-methoxy-3-methyl-2-{[4-(trifluoromethoxy)phenyl]-imino}-2,3-dihydro-1H-benzimidazol-1-yl)methyl]-N-1H-tetrazol-5-ylbenzoate

There total 1 articles about methyl 4-[(6-chloro-4-methoxy-3-methyl-2-{[4-(trifluoromethoxy)phenyl]-imino}-2,3-dihydro-1H-benzimidazol-1-yl)methyl]-N-1H-tetrazol-5-ylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 859877-52-4
5-chloro-7-methoxy-1-methyl-N-[4-(trifluoromethoxy)phenyl]-1H-benzimidazol-2-amine

: 2417-72-3
Methyl 4-(bromomethyl)benzoate

: 859877-53-5
methyl 4-[(6-chloro-4-methoxy-3-methyl-2-{[4-(trifluoromethoxy)phenyl]-imino}-2,3-dihydro-1H-benzimidazol-1-yl)methyl]-N-1H-tetrazol-5-ylbenzoate

Guidance literature:: In acetonitrile; at 80 ℃; for 40h;

Reference yield:

: 859877-53-5
methyl 4-[(6-chloro-4-methoxy-3-methyl-2-{[4-(trifluoromethoxy)phenyl]-imino}-2,3-dihydro-1H-benzimidazol-1-yl)methyl]-N-1H-tetrazol-5-ylbenzoate

: C₂₄H₁₉ClF₃N₃O₄

Guidance literature:: methyl 4-[(6-chloro-4-methoxy-3-methyl-2-{[4-(trifluoromethoxy)phenyl]-imino}-2,3-dihydro-1H-benzimidazol-1-yl)methyl]-N-1H-tetrazol-5-ylbenzoate; With lithium hydroxide; water; In 1,4-dioxane; at 40 ℃; for 1h;

In 1,4-dioxane; ethyl acetate; pH=7; Aqueous phosphate buffer;

Reference yield:

: 859877-53-5
methyl 4-[(6-chloro-4-methoxy-3-methyl-2-{[4-(trifluoromethoxy)phenyl]-imino}-2,3-dihydro-1H-benzimidazol-1-yl)methyl]-N-1H-tetrazol-5-ylbenzoate

: 859877-54-6
methyl 4-[(6-chloro-4-hydroxy-3-methyl-2-{[4-(trifluoromethoxy)phenyl]-imino}-2,3-dihydro-1H-benzimidazol-1-yl)methyl]-N-1H-tetrazol-5-ylbenzoate

Guidance literature:: methyl 4-[(6-chloro-4-methoxy-3-methyl-2-{[4-(trifluoromethoxy)phenyl]-imino}-2,3-dihydro-1H-benzimidazol-1-yl)methyl]-N-1H-tetrazol-5-ylbenzoate; With boron tribromide; In dichloromethane; at -78 ℃; for 1.5h;

With methanol; In dichloromethane; at -78 ℃;