Methyl 4-(bromomethyl)benzoate

Base Information

• Chemical Name: Methyl 4-(bromomethyl)benzoate
• CAS No.: 2417-72-3
• Molecular Formula: C9H9BrO2
• Molecular Weight: 229.073
• Hs Code.: 29163990
• European Community (EC) Number: 607-335-7
• NSC Number: 83959
• UNII: C9GY6V54X6
• DSSTox Substance ID: DTXSID4049406
• Nikkaji Number: J33.623H
• Wikidata: Q72488641
• ChEMBL ID: CHEMBL3183843
• Mol file: 2417-72-3.mol

Synonyms:Methyl 4-(bromomethyl)benzoate;2417-72-3;Methyl 4-bromomethylbenzoate;4-bromomethylbenzoic acid methyl ester;4-(Bromomethyl)benzoic Acid Methyl Ester;Benzoic acid, 4-(bromomethyl)-, methyl ester;methyl4-(bromomethyl)benzoate;MFCD00032453;methyl p-(bromomethyl)benzoate;methyl-4-(bromomethyl)benzoate;p-(Methoxycarbonyl)benzyl bromide;4-Bromomethyl benzoic acid methyl ester;methyl 4-bromomethyl benzoate;C9GY6V54X6;DTXSID4049406;NSC-83959;4-(Methoxycarbonyl)benzyl bromide;4-carbomethoxybenzyl bromide;Methyl alpha-Bromo-p-toluate;4-bromomethyl-benzoic acid methyl ester;methyl-4-bromomethylbenzoate;(4-carbmethoxy)benzylbromide;NCIOpen2_004628;UNII-C9GY6V54X6;SCHEMBL33494;methyl-4(bromomethyl)benzoate;(4-carbmethoxy) benzylbromide;p-methoxycarbonylbenzyl bromide;4-methoxycarbonylbenzyl bromide;4-(Carbomethoxy)benzyl bromide;Methy 4-(Bromomethyl)Benzoate;methyl (4-bromomethyl)benzoate;methy 4-(bromomethyl) benzoate;methyl 4-(bromomethy) benzoate;Methyl 4-(bromomethy)-benzoate;4-methoxycarbonyl-benzyl bromide;CHEMBL3183843;DTXCID3029366;methyl 4- (bromomethyl)benzoate;methyl 4-(bromomethyl) benzoate;methyl 4-(bromomethyl)-benzoate;methyl-4-(bromomethyl)-benzoate;Methyl 4-(bromo-methyl)benzoate;4-methoxy carbonyl benzyl bromide;4-(bromomethyl)benzoic acid methyl;BCP30275;NSC83959;STR03614;Tox21_202815;AB7470;NSC 83959;STK397278;[4-(methoxycarbonyl)-benzyl]-bromide;p-bromomethylbenzoic acid methyl ester;4bromomethyl-benzoic acid methyl ester;AKOS000119636;Methyl 4-(bromomethyl)benzoate, 98%;AC-4378;alpha-Bromo-p-toluic Acid Methyl Ester;CS-W008845;NCGC00260361-01;NCGC00320831-01;4-(bromo-methyl)benzoic acid methyl ester;4-(bromomethyl)benzoic acid, methyl ester;CAS-2417-72-3;p-Toluic acid, alpha-bromo-, methyl ester;4-(bromo-methyl)-benzoic acid methyl ester;A4993;AM20030428;B2053;BB 0258786;FT-0616713;EN300-18210;AB01315911-02;Q-102004;Z57358719;F1019-0028;methyl 4-(bromomethyl)benzoate

Chemical Property of Methyl 4-(bromomethyl)benzoate

Chemical Property:

• Appearance/Colour: white to off-white crystalline powder
• Vapor Pressure: 0.00063mmHg at 25°C
• Melting Point: 57-58 °C(lit.)
• Refractive Index: 1.559
• Boiling Point: 309.7 °C at 760 mmHg
• Flash Point: 127.8 °C
• PSA: 26.30000
• Density: 1.46 g/cm³
• LogP: 2.36810
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive.: Lachrymatory
• Water Solubility.: Lowly soluble in water, highly soluble in ethanol and ether, not soluble in halogenated organic solvents
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 227.97859
• Heavy Atom Count: 12
• Complexity: 151

Purity/Quality:

99% ^*data from raw suppliers

4-(Bromomethyl)benzoicAcidMethylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 22-34-43
• Safety Statements: 26-36/37/39-45-25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: COC(=O)C1=CC=C(C=C1)CBr
• Uses: Methyl 4-(bromomethyl)benzoate is an ester derivative of a bromoalkylated benzoic acid. Methyl 4-(bromomethyl)benzoate is used in the preparation of potential anti-HIV agents. It i s also used as a catalyst for rearrangement of benzylthiothiazoline derivatives in the preparation aldose reductase inhibitors. Methyl 4-(bromomethyl)benzoate is used in the preparation of potential anti-HIV agents. It i s also used as a catalyst for rearrangement of benzylthiothiazoline derivatives in the preparation aldose reductase inhibitors.

Technology Process of Methyl 4-(bromomethyl)benzoate

There total 27 articles about Methyl 4-(bromomethyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + 4-bromomethylbenzoic Acid (6232-88-8) → Methyl 4-(bromomethyl)benzoate (2417-72-3)

Guidance literature:

In tetrahydrofuran; diethyl ether; at 0 ℃;

DOI:10.1016/j.bmc.2011.03.044

Reference yield: 96.0%

methanol (67-56-1) + 4-bromomethylbenzoic Acid (6232-88-8) → Methyl 4-(bromomethyl)benzoate (2417-72-3)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 16h;

DOI:10.1002/chem.201701204

Reference yield: 91.0%

methanol (67-56-1) + 4-bromomethylbenzoyl chloride (52780-16-2) → Methyl 4-(bromomethyl)benzoate (2417-72-3)

Guidance literature:

With sodium hydrogencarbonate; at 20 ℃; for 4h;

DOI:10.1021/ja993570b

upstream raw materials:

methanol

4-bromomethylbenzoyl chloride

4-bromomethylbenzoic Acid

para-chlorotoluene

Downstream raw materials:

methyl 4-formylbenzoate

methyl 4-(cyanomethyl)benzoate

methyl 4-(iodomethyl)benzoate

dimethyl 4,4’-(azanediylbis(methylene))dibenzoate

Refernces

Synthesis and combined properties of novel fluorinated cationic surfactants derived from hexafluoropropylene dimer

10.1016/j.cclet.2018.04.017

The study focuses on the synthesis and evaluation of three novel fluorinated cationic surfactants derived from hexafluoropropylene dimer. These surfactants, characterized by branched short fluorinated tails and ammonium oxide polar groups, were found to possess excellent surface properties, reducing the surface tension of water to below 20.00 mN/m at their critical micelle concentrations (CMC). The study also explored the surfactants' compatibility when mixed with other types of surfactants, such as SDS, AOS, APG, and LAB, which are commonly used in fire-fighting foams. The combination of these novel fluorinated surfactants with hydrocarbon surfactants resulted in even lower CMC and surface tension values, suggesting their potential as sustainable alternatives to perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) in the formulation of aqueous film-forming foams (AFFFs) for firefighting applications. The research was supported by the National Natural Science Foundation of China and the Science and Technology Commission of Shanghai Municipality.

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 2417-72-3 Methyl 4-(bromomethyl)benzoate

Send

Send

Metric Ton KG G Pound L ML

Send

Send