methyl rac-9-(ethylidenedioxy)-15-(phenylsulfenyl)-14(E)-prostanoate

Base Information

• Chemical Name: methyl rac-9-(ethylidenedioxy)-15-(phenylsulfenyl)-14(E)-prostanoate
• CAS No.: 84700-67-4
• Molecular Formula: C₂₉H₄₄O₅S
• Molecular Weight: 504.731
• Mol file: 84700-67-4.mol

Synonyms:methyl rac-9-(ethylidenedioxy)-15-(phenylsulfenyl)-14(E)-prostanoate

Chemical Property of methyl rac-9-(ethylidenedioxy)-15-(phenylsulfenyl)-14(E)-prostanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl rac-9-(ethylidenedioxy)-15-(phenylsulfenyl)-14(E)-prostanoate

There total 5 articles about methyl rac-9-(ethylidenedioxy)-15-(phenylsulfenyl)-14(E)-prostanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

ethylene glycol (107-21-1) + methyl rac-9-oxo-15-(phenylsulfinyl)-14(E)-prostanoate (84700-65-2) → methyl rac-9-(ethylidenedioxy)-15-(phenylsulfenyl)-14(E)-prostanoate (84700-67-4)

Guidance literature:

With toluene-4-sulfonic acid; In benzene; for 3h; Heating;

Reference yield:

2-(6-methoxycarbonylhexyl)cyclopent-2-en-1-one (34546-57-1) → methyl rac-9-(ethylidenedioxy)-15-(phenylsulfenyl)-14(E)-prostanoate (84700-67-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) diisopropylamine, butyllithium / 1) THF, hexane, -78 deg C, 40 min, 2) -78 deg C, 4 h.

2: 85 percent / p-toluene sulfonic acid / benzene / 3 h / Heating

With n-butyllithium; toluene-4-sulfonic acid; diisopropylamine; In benzene;

Reference yield:

phenyl 1-vinylhexyl sulfoxide (86894-53-3) → methyl rac-9-(ethylidenedioxy)-15-(phenylsulfenyl)-14(E)-prostanoate (84700-67-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) diisopropylamine, butyllithium / 1) THF, hexane, -78 deg C, 40 min, 2) -78 deg C, 4 h.

2: 85 percent / p-toluene sulfonic acid / benzene / 3 h / Heating

With n-butyllithium; toluene-4-sulfonic acid; diisopropylamine; In benzene;

upstream raw materials:

ethylene glycol

methyl rac-9-oxo-15-(phenylsulfinyl)-14(E)-prostanoate

(E)-oct-2-en-1-ol

2-(6-methoxycarbonylhexyl)cyclopent-2-en-1-one

Downstream raw materials:

rac-9-(ethylidenedioxy)-15-(phenylsulfenyl)-14(E)-prostanoic acid