6-(1-benzyl-5-methyl-4-phenyl-1H-imidazol-2-yl)-N,3-dimethyl[1,2,4]triazolo[4,3-a]pyrazin-8-amine

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Chemical Name:6-(1-benzyl-5-methyl-4-phenyl-1H-imidazol-2-yl)-N,3-dimethyl[1,2,4]triazolo[4,3-a]pyrazin-8-amine
CAS No.:1610044-83-1
Molecular Formula:C₂₄H₂₃N₇
Molecular Weight:409.494
Hs Code.:

Synonyms:6-(1-benzyl-5-methyl-4-phenyl-1H-imidazol-2-yl)-N,3-dimethyl[1,2,4]triazolo[4,3-a]pyrazin-8-amine

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Chemical Property of 6-(1-benzyl-5-methyl-4-phenyl-1H-imidazol-2-yl)-N,3-dimethyl[1,2,4]triazolo[4,3-a]pyrazin-8-amine

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Technology Process of 6-(1-benzyl-5-methyl-4-phenyl-1H-imidazol-2-yl)-N,3-dimethyl[1,2,4]triazolo[4,3-a]pyrazin-8-amine

There total 3 articles about 6-(1-benzyl-5-methyl-4-phenyl-1H-imidazol-2-yl)-N,3-dimethyl[1,2,4]triazolo[4,3-a]pyrazin-8-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

: 1610045-54-9
3-methyl-8-(methylamino)[1,2,4]triazolo[4,3-a]pyrazine-6-carbaldehyde

: 25355-34-4
1-phenyl-propane-1,2-dione 1-oxime

: 100-46-9
benzylamine

: 1610044-83-1
6-(1-benzyl-5-methyl-4-phenyl-1H-imidazol-2-yl)-N,3-dimethyl[1,2,4]triazolo[4,3-a]pyrazin-8-amine

Guidance literature:: 3-methyl-8-(methylamino)[1,2,4]triazolo[4,3-a]pyrazine-6-carbaldehyde; 1-phenyl-propane-1,2-dione 1-oxime; benzylamine; In acetic acid; at 120 ℃; for 2h;

With hydrogen; In tetrahydrofuran; at 25 ℃; for 48h; under 3000.3 Torr;

Reference yield:

: C₈H₁₁N₅O

: 1610044-83-1
6-(1-benzyl-5-methyl-4-phenyl-1H-imidazol-2-yl)-N,3-dimethyl[1,2,4]triazolo[4,3-a]pyrazin-8-amine

Guidance literature:: Multi-step reaction with 2 steps

1.1: manganese(IV) oxide / dichloromethane; chloroform / 96 h / 50 °C

2.1: acetic acid / 2 h / 120 °C

2.2: 48 h / 25 °C / 3000.3 Torr

With manganese(IV) oxide; In dichloromethane; chloroform; acetic acid;

Reference yield:

: 1610045-47-0
3-methyl-8-(methylamino)-[1,2,4]triazolo[4,3-a]pyrazine-6-carboxylic acid

: 1610044-83-1
6-(1-benzyl-5-methyl-4-phenyl-1H-imidazol-2-yl)-N,3-dimethyl[1,2,4]triazolo[4,3-a]pyrazin-8-amine

Guidance literature:: Multi-step reaction with 3 steps

1.1: borane-THF / tetrahydrofuran / 16 h / 50 °C

1.2: pH 7

2.1: manganese(IV) oxide / dichloromethane; chloroform / 96 h / 50 °C

3.1: acetic acid / 2 h / 120 °C

3.2: 48 h / 25 °C / 3000.3 Torr

With manganese(IV) oxide; borane-THF; In tetrahydrofuran; dichloromethane; chloroform; acetic acid;