Paroxetine maleate

Base Information

Chemical Name:Paroxetine maleate
CAS No.:64006-44-6
Molecular Formula:C19H20NO3F^.C4H4O4
Molecular Weight:445.444
Hs Code.:
European Community (EC) Number:636-343-3
UNII:F726G2563Q
DSSTox Substance ID:DTXSID9042590
Wikidata:Q27133113
ChEMBL ID:CHEMBL1449490

Synonyms:Aropax;BRL 29060;BRL-29060;BRL29060;FG 7051;FG-7051;FG7051;Paroxetine;Paroxetine Acetate;Paroxetine Hydrochloride;Paroxetine Hydrochloride Anhydrous;Paroxetine Hydrochloride Hemihydrate;Paroxetine Hydrochloride, Hemihydrate;Paroxetine Maleate;Paroxetine, cis-(+)-Isomer;Paroxetine, cis-(-)-Isomer;Paroxetine, trans-(+)-Isomer;Paxil;Seroxat

Suppliers and Price of Paroxetine maleate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Paroxetine maleate
10mg
$ 389.00

TRC
ParoxetineMaleate
10mg
$ 85.00

Tocris
Paroxetinemaleate ≥99%(HPLC)
50
$ 616.00

Tocris
Paroxetinemaleate ≥99%(HPLC)
10
$ 151.00

Sigma-Aldrich
Paroxetine maleate salt ≥98% (HPLC), solid
10mg
$ 135.00

Sigma-Aldrich
Paroxetine maleate solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
1 mL
$ 28.80

Sigma-Aldrich
Paroxetine maleate solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material
916-1ml
$ 27.90

Sigma-Aldrich
Paroxetine maleate salt ≥98% (HPLC), solid
50mg
$ 534.00

Medical Isotopes, Inc.
Paroxetinemaleate
1 mg
$ 525.00

ApexBio Technology
Paroxetinemaleate
10mg
$ 219.00

Total 22 raw suppliers

Chemical Property of Paroxetine maleate

Chemical Property:

Appearance/Colour:white solid
Vapor Pressure:2.39E-08mmHg at 25°C
Melting Point:136-138°C
Boiling Point:451.7 °C at 760 mmHg
Flash Point:227 °C
PSA：114.32000
Density:1.213 g/cm³
LogP:3.36710
Storage Temp.:Store at RT
Solubility.:DMSO: ~12 mg/mL
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:6
Exact Mass:445.15368027
Heavy Atom Count:32
Complexity:521

Purity/Quality:

98%,99%, ^*data from raw suppliers

Paroxetine maleate ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn,T,F
Statements: 22-36/37/38-39/23/24/25-23/24/25-11
Safety Statements: 26-36-45-36/37-16-7

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1CNCC(C1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4.C(=CC(=O)O)C(=O)O
Isomeric SMILES:C1CNC[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4.C(=C\C(=O)O)\C(=O)O
Uses Paroxetine maleate is a selective serotonin uptake inhibitor.

Technology Process of Paroxetine maleate

There total 2 articles about Paroxetine maleate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 110-16-7,26099-09-2
maleic acid

: 110429-35-1,130855-30-0
(-)-paroxetine hydrochloride

: 64006-44-6
paroxetine maleate

Guidance literature:: maleic acid; With sodium hydroxide; In water;

(-)-paroxetine hydrochloride; In ethanol; water; for 48h;
DOI:10.1039/c8ce02076k