(S)-ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(m-tolyl)propanoate

Base Information

Chemical Name:(S)-ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(m-tolyl)propanoate
CAS No.:1429299-19-3
Molecular Formula:C₁₈H₂₇BO₄
Molecular Weight:318.221
Hs Code.:

Synonyms:(S)-ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(m-tolyl)propanoate

Suppliers and Price of (S)-ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(m-tolyl)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(m-tolyl)propanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(m-tolyl)propanoate

There total 5 articles about (S)-ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(m-tolyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: ethyl (Z)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(m-tolyl)-acrylate

: 1429299-19-3
(S)-ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(m-tolyl)propanoate

Guidance literature:: With bis(norbornadiene)rhodium(l)tetrafluoroborate; ZhaoPhos; hydrogen; In dichloromethane; at 30 ℃; for 6h; under 38002.6 Torr; enantioselective reaction; Autoclave;
DOI:10.1002/adsc.201900161

Reference yield: 72.0%

: 50556-03-1,62174-97-4
(E)-ethyl 3-(m-tolyl)acrylate

: 73183-34-3
bis(pinacol)diborane

: 1429299-19-3
(S)-ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(m-tolyl)propanoate

Guidance literature:: With C₂₄H₃₅N₂O₇Rh; sodium t-butanolate; In toluene; at 80 ℃; for 0.5h; enantioselective reaction; Inert atmosphere;
DOI:10.1016/j.tet.2013.02.086

Reference yield:

: 50556-03-1
3-m-tolyl-acrylic acid ethyl ester

: 73183-34-3
bis(pinacol)diborane

: 1429299-19-3
(S)-ethyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(m-tolyl)propanoate

Guidance literature:: bis(pinacol)diborane; With copper(I) oxide; C₃₁H₃₄N₃O⁽¹⁺⁾*Cl^(1-); caesium carbonate; In 1,2-dimethoxyethane; at 20 ℃; for 0.166667h; Schlenk technique; Inert atmosphere;

3-m-tolyl-acrylic acid ethyl ester; In methanol; 1,2-dimethoxyethane; at 0 ℃; for 4h; enantioselective reaction;
DOI:10.1021/jo5021135