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L-isoleucyl-L-phenylalanine methyl amide

Base Information Edit
  • Chemical Name:L-isoleucyl-L-phenylalanine methyl amide
  • CAS No.:871917-47-4
  • Molecular Formula:C16H25N3O2
  • Molecular Weight:291.393
  • Hs Code.:
  • Mol file:871917-47-4.mol
L-isoleucyl-L-phenylalanine methyl amide

Synonyms:L-isoleucyl-L-phenylalanine methyl amide

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The product has achieved commercial mass production*data from LookChem market partment
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Chemical Property of L-isoleucyl-L-phenylalanine methyl amide Edit
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Technology Process of L-isoleucyl-L-phenylalanine methyl amide

There total 5 articles about L-isoleucyl-L-phenylalanine methyl amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With hydrogenchloride; In 1,4-dioxane; for 1h; Ambient temperature;
DOI:10.1021/jm00099a008
Guidance literature:
Multi-step reaction with 2 steps
1.1: 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride; HOBt / CH2Cl2 / 0.5 h / 0 °C
1.2: CH2Cl2
2.1: 373 mg / trifluoroacetic acid / CH2Cl2 / 0.67 h / 20 °C
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; In dichloromethane;
DOI:10.1021/jo0517848
Guidance literature:
Multi-step reaction with 4 steps
1.1: 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride; HOBt / CH2Cl2 / 0.5 h / 0 °C
1.2: CH2Cl2; methanol
2.1: 105 mg / trifluoroacetic acid / CH2Cl2 / 0.67 h / 20 °C
3.1: 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride; HOBt / CH2Cl2 / 0.5 h / 0 °C
3.2: CH2Cl2
4.1: 373 mg / trifluoroacetic acid / CH2Cl2 / 0.67 h / 20 °C
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; In dichloromethane;
DOI:10.1021/jo0517848
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