(3S,6R)-1-benzyl 3-methyl 6-(hydroxymethyl)piperidine-1,3-dicarboxylate

Base Information

Chemical Name:(3S,6R)-1-benzyl 3-methyl 6-(hydroxymethyl)piperidine-1,3-dicarboxylate
CAS No.:1620675-50-4
Molecular Formula:C₁₆H₂₁NO₅
Molecular Weight:307.346
Hs Code.:

Synonyms:(3S,6R)-1-benzyl 3-methyl 6-(hydroxymethyl)piperidine-1,3-dicarboxylate

Suppliers and Price of (3S,6R)-1-benzyl 3-methyl 6-(hydroxymethyl)piperidine-1,3-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3S,6R)-1-benzyl 3-methyl 6-(hydroxymethyl)piperidine-1,3-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S,6R)-1-benzyl 3-methyl 6-(hydroxymethyl)piperidine-1,3-dicarboxylate

There total 13 articles about (3S,6R)-1-benzyl 3-methyl 6-(hydroxymethyl)piperidine-1,3-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 56026-36-9
methyl 6-(hydroxymethyl)nicotinate

: 1620675-50-4
(3S,6R)-1-benzyl 3-methyl 6-(hydroxymethyl)piperidine-1,3-dicarboxylate

Guidance literature:: Multi-step reaction with 5 steps

1: dmap; triethylamine / dichloromethane / 3 h / 20 °C

2: sodium cyanoborohydride; acetic acid / 4 h / 0 - 30 °C

3: tetrahydrofuran; water / 18 h / 20 °C

4: sodium hydrogencarbonate; potassium carbonate / methanol / 1 h / 20 °C

5: Chiraipak AD-Fl 25050mnmi.D,, / carbon dioxide; ethanol / 75007.5 Torr / Supercritical conditions; Resolution of racemate; liquid CO₂

With dmap; sodium cyanoborohydride; sodium hydrogencarbonate; potassium carbonate; acetic acid; triethylamine; In tetrahydrofuran; methanol; ethanol; dichloromethane; carbon dioxide; water;

Reference yield:

: (trans)-1-benzyl 3-methyl 6-(hydroxymethyl)piperidine-1,3-dicarboxylate

: 1620675-51-5
(3R,6S)-1-benzyl 3-methyl 6-(hydroxymethyl)piperidine-1,3-dicarboxylate

: 1620675-50-4
(3S,6R)-1-benzyl 3-methyl 6-(hydroxymethyl)piperidine-1,3-dicarboxylate

Guidance literature:: With AD column; In methanol; carbon dioxide; Resolution of racemate; liquid CO₂;

Reference yield:

: 63362-34-5
methyl 6-(acetoxymethyl)nicotinate

: 1620675-50-4
(3S,6R)-1-benzyl 3-methyl 6-(hydroxymethyl)piperidine-1,3-dicarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: acetic acid; sodium cyanoborohydride / 20 °C

1.2: 0 - 20 °C

2.1: hydrogenchloride / methanol / Reflux

3.1: AD column / methanol; carbon dioxide / Resolution of racemate; liquid CO₂

With hydrogenchloride; sodium cyanoborohydride; acetic acid; In methanol; carbon dioxide;