2-(aminomethylidene)propanedial

Base Information

• Chemical Name: 2-(aminomethylidene)propanedial
• CAS No.: 20052-93-1
• Molecular Formula: C4H5NO2
• Molecular Weight: 234.255
• Mol file: 20052-93-1.mol

Synonyms:VZLSSMVWAAWINT-UHFFFAOYSA;2,3,4-pentanetrione;2,3,4-Pentanetrione, 3-[(2-methoxyphenyl)hydrazone];

Chemical Property of 2-(aminomethylidene)propanedial

Chemical Property:

• Boiling Point: 360.7±44.0 °C(Predicted)
• PSA: 60.16000
• Density: 1.14±0.1 g/cm3(Predicted)
• LogP: -0.07290

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(aminomethylidene)propanedial

There total 4 articles about 2-(aminomethylidene)propanedial which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(Z)-4-trimethylsiloxypent-3-en-2-one (25145-04-4) + 1-(2-methoxyphenyl)-2-(methylsulfonyl)diazene → 3-(2-(2-methoxyphenyl)hydrazono)pentane-2,4-dione (20052-93-1)

Guidance literature:

With sodium hydrogencarbonate; In acetonitrile; for 20h; Irradiation;

DOI:10.1002/adsc.201901424

Reference yield: 82.0%

2-methoxy-phenylamine (90-04-0) + acetylacetone (123-54-6,81235-32-7) → 3-(2-(2-methoxyphenyl)hydrazono)pentane-2,4-dione (20052-93-1)

Guidance literature:

2-methoxy-phenylamine; With hydrogenchloride; sodium nitrite; In water; at 0 - 5 ℃; for 0.5h;

acetylacetone; With sodium acetate; In methanol; water; at 20 ℃;

DOI:10.1002/chem.201902150

Reference yield:

2-methoxybenzenediazonium chloride (3425-23-8) + acetylacetone (123-54-6,81235-32-7) → 3-(2-(2-methoxyphenyl)hydrazono)pentane-2,4-dione (20052-93-1)

Guidance literature:

With sodium acetate; In ethanol; at 0 ℃;

DOI:10.1246/bcsj.66.555

upstream raw materials:

2-methoxy-phenylamine

acetylacetone

2-methoxybenzenediazonium chloride

(Z)-4-trimethylsiloxypent-3-en-2-one

Downstream raw materials:

4-(2-methoxy-phenylazo)-3,5-dimethyl-isoxazole

2-[4-(2-methoxy-phenylazo)-3,5-dimethyl-pyrazol-1-yl]-4,6-dimethyl-pyrimidine

3-(N-Nitro-N-2-methoxyphenylhydrazono)pentane-2,4-dione

4-(2-Methoxy-phenylazo)-3,5-dimethyl-pyrazole-1-carbothioic acid phenylamide