C₂₀H₁₉BrO₃

Base Information

• Chemical Name: C₂₀H₁₉BrO₃
• CAS No.: 1318697-48-1
• Molecular Formula: C₂₀H₁₉BrO₃
• Molecular Weight: 387.273
• Mol file: 1318697-48-1.mol

Synonyms:C₂₀H₁₉BrO₃

Chemical Property of C₂₀H₁₉BrO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₁₉BrO₃

There total 5 articles about C₂₀H₁₉BrO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C26H33BrO3Si → C20H19BrO3 (1318697-48-1)

Guidance literature:

With pyridine hydrogenfluoride; In acetonitrile; for 16h; Inert atmosphere;

DOI:10.1021/ja205068j

Reference yield:

C21H25BrO2Si (1318697-37-8) → C20H19BrO3 (1318697-48-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.37 h / -78 °C / Inert atmosphere

1.2: 1 h / -78 - 20 °C / Inert atmosphere

2.1: pyridine hydrogenfluoride / acetonitrile / 16 h / Inert atmosphere

With sodium hexamethyldisilazane; pyridine hydrogenfluoride; In tetrahydrofuran; acetonitrile;

DOI:10.1021/ja205068j

Reference yield:

4-bromo-benzaldehyde (1122-91-4) → C20H19BrO3 (1318697-48-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: tetrahydrofuran; diethyl ether / 3 h / 20 °C / Inert atmosphere

1.2: 0.52 h / -78 °C / Inert atmosphere

2.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.37 h / -78 °C / Inert atmosphere

2.2: 1 h / -78 - 20 °C / Inert atmosphere

3.1: pyridine hydrogenfluoride / acetonitrile / 16 h / Inert atmosphere

With sodium hexamethyldisilazane; pyridine hydrogenfluoride; In tetrahydrofuran; diethyl ether; acetonitrile;

DOI:10.1021/ja205068j

upstream raw materials:

C₂₁H₂₅BrO₂Si

pivaloyl chloride

4-bromo-benzaldehyde

Downstream raw materials:

C₂₀H₁₉BrO₃