Pivaloyl chloride

Base Information Edit

Chemical Name:Pivaloyl chloride
CAS No.:3282-30-2
Deprecated CAS:1612831-59-0
Molecular Formula:C5H9ClO
Molecular Weight:120.579
Hs Code.:29159080
European Community (EC) Number:221-921-6
UN Number:2438
UNII:JQ82J0O21T
DSSTox Substance ID:DTXSID4027529
Nikkaji Number:J33.810I
Wikipedia:Pivaloyl_chloride
Wikidata:Q2017164
ChEMBL ID:CHEMBL3183814
Mol file:3282-30-2.mol

Synonyms:pivaloyl chloride

Suppliers and Price of Pivaloyl chloride

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,2-DimethylpropanoylChloride
100 ml
$ 135.00

Sigma-Aldrich
Trimethylacetyl chloride 99%
100ml
$ 20.40

Sigma-Aldrich
Trimethylacetyl chloride 99%
5ml
$ 20.30

Sigma-Aldrich
Trimethylacetyl chloride 99%
500ml
$ 67.00

Medical Isotopes, Inc.
2,2-DimethylpropanoylChloride
100 ml
$ 625.00

Alfa Aesar
Trimethylacetyl chloride, 98+%
2500ml
$ 216.00

Alfa Aesar
Trimethylacetyl chloride, 98+%
500ml
$ 58.60

Alfa Aesar
Trimethylacetyl chloride, 98+%
100ml
$ 18.00

Total 134 raw suppliers

Chemical Property of Pivaloyl chloride Edit

Chemical Property:

Appearance/Colour:colorless to yellow liquid
Vapor Pressure:36 mm Hg ( 20 °C)
Melting Point:-56 °C
Refractive Index:n20/D 1.412(lit.)
Boiling Point:107.2 °C at 760 mmHg
Flash Point:8.9 °C
PSA：17.07000
Density:1.008 g/cm³
LogP:1.79790
Storage Temp.:Store at RT.
Sensitive.:Moisture Sensitive
Solubility.:Miscible with acetonitrile.
Water Solubility.:Hydrolysis
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:120.0341926
Heavy Atom Count:7
Complexity:80.6
Transport DOT Label:Poison Inhalation Hazard Corrosive Flammable Liquid

Purity/Quality:

99% ^*data from raw suppliers

2,2-DimethylpropanoylChloride ^*data from reagent suppliers

Safty Information:

Pictogram(s): F, T+, T
Hazard Codes:F,T+,T
Statements: 11-14-22-26-34-23
Safety Statements: 16-26-36/37/39-45-38-28A

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Toxic Gases & Vapors -> Acid Halides
Canonical SMILES:CC(C)(C)C(=O)Cl
Uses Widely used N-acylating agent for amines,1 Schiff bases,2 and pyrrolidinones3 as well as O-acylating agent for alcohols,4 lactones,5 and saccharides.6 Trimethylacetyl chloride is used as a precursor in the preparation of tert-butyl peroxypivalate, guttiferon A derivatives, which is potential for the treatment of malaria. It is used as a raw material in the production of synthetic acidamide medicament and phenol ester medicament. In addition to this, it is used for the synthesis of active pharmaceutical ingredients such as aminobenzylpenicilin, cephalexin, cefazolin, dipivefrin and dipivalyl epinephrine. It is also used in heavy polymerization, N-acylating agent for amines, Schiff bases, pyrrolidinones as well as an O-acylating agent for alcohols, lactones and saccharides.

Technology Process of Pivaloyl chloride

There total 31 articles about Pivaloyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%