Galβ1-3GalNAcα-O-TVPAAV-D-Val-VA

Base Information

• Chemical Name: Galβ1-3GalNAcα-O-TVPAAV-D-Val-VA
• CAS No.: 1070177-86-4
• Molecular Formula: C₅₂H₉₀N₁₀O₂₁
• Molecular Weight: 1191.34
• Mol file: 1070177-86-4.mol

Synonyms:Galβ1-3GalNAcα-O-TVPAAV-D-Val-VA

Chemical Property of Galβ1-3GalNAcα-O-TVPAAV-D-Val-VA

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Galβ1-3GalNAcα-O-TVPAAV-D-Val-VA

There total 1 articles about Galβ1-3GalNAcα-O-TVPAAV-D-Val-VA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Fmoc-Val-OH (68858-20-8) + N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine (35661-39-3,136132-75-7) + Fmoc-Pro-OH (71989-31-6) + N-(9-fluorenylmethoxycarbonyl)-D-valine (84624-17-9) + Nα-fluoren-9-ylmethoxycarbonyl-O-[O-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-2-acetamido-4,6-di-O-acetyl-2-deoxy-α-D-galactopyranosyl]-L-threonine (125760-33-0) → Galβ1-3GalNAcα-O-TVPAAV-D-Val-VA (1070177-86-4)

Guidance literature:

N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine; Automated synthesizer; solid phase reaction;

With piperidine; In 1-methyl-pyrrolidin-2-one; Automated synthesizer; solid phase reaction;

Fmoc-Val-OH; Fmoc-Pro-OH; N-(9-fluorenylmethoxycarbonyl)-D-valine; N^α-fluoren-9-ylmethoxycarbonyl-O-[O-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)-(1->3)-2-acetamido-4,6-di-O-acetyl-2-deoxy-α-D-galactopyranosyl]-L-threonine; Further stages;

DOI:10.1021/jm8002763

upstream raw materials:

Fmoc-Val-OH

N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

Fmoc-Pro-OH

N-(9-fluorenylmethoxycarbonyl)-D-valine