FMOC-D-Valine

Base Information

Chemical Name:FMOC-D-Valine
CAS No.:84624-17-9
Molecular Formula:C20H21NO4
Molecular Weight:339.391
Hs Code.:2924 29 70
European Community (EC) Number:837-857-2
Nikkaji Number:J1.101.660J
Mol file:84624-17-9.mol

Synonyms:FMOC-D-VAL-OH;N-alpha-(9-Fluorenylmethyloxycarbonyl)-D-valine;

Suppliers and Price of FMOC-D-Valine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Fmoc-D-Val-OH
10g
$ 350.00

Usbiological
Fmoc-D-valine 99+%
1g
$ 156.00

TRC
N-Fmoc-D-valine
25g
$ 60.00

TRC
N-Fmoc-D-valine
10g
$ 45.00

TCI Chemical
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-valine >98.0%(HPLC)(T)
5g
$ 24.00

TCI Chemical
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-valine >98.0%(HPLC)(T)
25g
$ 116.00

SynQuest Laboratories
D-Valine, N-Fmoc protected 99%
100 g
$ 122.00

Sigma-Aldrich
Fmoc-D-Val-OH Novabiochem?
5 g
$ 79.80

Sigma-Aldrich
Fmoc-D-Val-OH Novabiochem . CAS 84624-17-9, molar mass 339.39 g/mol., Novabiochem
8521520005
$ 77.10

Sigma-Aldrich
Fmoc-D-Val-OH Novabiochem?
25 g
$ 323.00

Total 119 raw suppliers

Chemical Property of FMOC-D-Valine

Chemical Property:

Appearance/Colour:white to light yellow crystal powder
Melting Point:143-144 °C(lit.)
Boiling Point:551.8±33.0 °C(Predicted)
PKA:3.90±0.10(Predicted)
PSA：75.63000
Density:1.229±0.06 g/cm3(Predicted)
LogP:4.02520
Storage Temp.:2-8°C
Solubility.:Chloroform (Slightly), DMF (Slightly), DMSO (Slightly), Methanol (Slightly)
Water Solubility.:Solubility in methanol (almost transparency). Slightly soluble in water.
XLogP3:4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:339.14705815
Heavy Atom Count:25
Complexity:470

Purity/Quality:

99% ^*data from raw suppliers

Fmoc-D-Val-OH ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Isomeric SMILES:CC(C)[C@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Uses N-Fmoc-D-valine is an N-Fmoc-protected form of D-Valine (V094200). D-Valine (an isomer of the essential amino acid L-Valine [V094205])exhibited inhibitory effects on fibroblasts that contaminated mammalian kidney cultures, allowing for selective growth epithelial cells. D-Valine is also known for its presence in the structure of Actinomycin D, an antitumour drug. D-Valine is naturally synthesized by Streptomyces antibioticus.

Technology Process of FMOC-D-Valine

There total 7 articles about FMOC-D-Valine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 640-68-6,25609-85-2,7004-03-7,921-10-8
D-Val-OH

: 28920-43-6
(fluorenylmethoxy)carbonyl chloride

: 84624-17-9
N-(9-fluorenylmethoxycarbonyl)-D-valine

Guidance literature:: With sodium carbonate; In 1,4-dioxane; at 0 - 20 ℃;

Reference yield:

: 126727-02-4
Fmoc-valine

: 68858-20-8
Fmoc-Val-OH

: 84624-17-9
N-(9-fluorenylmethoxycarbonyl)-D-valine

Guidance literature:: With trifluoroacetic acid; In hexane; isopropyl alcohol; at 25 ℃; Reagent/catalyst; Resolution of racemate;
DOI:10.1002/bkcs.11694