methyl 2-{2-[2-(1-benzyl-1H-indol-3-yl)ethylcarbamoyl]hydrazino}-2-oxoacetate

Base Information

• Chemical Name: methyl 2-{2-[2-(1-benzyl-1H-indol-3-yl)ethylcarbamoyl]hydrazino}-2-oxoacetate
• CAS No.: 909707-94-4
• Molecular Formula: C₂₁H₂₂N₄O₄
• Molecular Weight: 394.43

Synonyms:methyl 2-{2-[2-(1-benzyl-1H-indol-3-yl)ethylcarbamoyl]hydrazino}-2-oxoacetate

Chemical Property of methyl 2-{2-[2-(1-benzyl-1H-indol-3-yl)ethylcarbamoyl]hydrazino}-2-oxoacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-{2-[2-(1-benzyl-1H-indol-3-yl)ethylcarbamoyl]hydrazino}-2-oxoacetate

There total 2 articles about methyl 2-{2-[2-(1-benzyl-1H-indol-3-yl)ethylcarbamoyl]hydrazino}-2-oxoacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

N-[2-(1-benzyl-1H-indol-3-yl)ethyl]-1H-imidazole-1-carboxamide (909707-93-3) + methyl hydrazino(oxo)acetate (63970-76-3) → methyl 2-{2-[2-(1-benzyl-1H-indol-3-yl)ethylcarbamoyl]hydrazino}-2-oxoacetate (909707-94-4)

Guidance literature:

With acetic acid; In tetrahydrofuran; for 16h; Heating;

DOI:10.1021/ja0612549

Reference yield:

N-benzyltryptamine (4307-98-6) → methyl 2-{2-[2-(1-benzyl-1H-indol-3-yl)ethylcarbamoyl]hydrazino}-2-oxoacetate (909707-94-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 76 percent / CH₂Cl₂; tetrahydrofuran / 20 °C

2: 82 percent / acetic acid / tetrahydrofuran / 16 h / Heating

With acetic acid; In tetrahydrofuran; dichloromethane;

DOI:10.1021/ja0612549

Reference yield: 69.0%

methyl 2-{2-[2-(1-benzyl-1H-indol-3-yl)ethylcarbamoyl]hydrazino}-2-oxoacetate (909707-94-4) → methyl 5-[2-(1-benzyl-1H-indol-3-yl)ethylamino]-1,3,4-oxadiazole-2-carboxylate (909707-95-5)

Guidance literature:

With triethylamine; p-toluenesulfonyl chloride; In dichloromethane; at 20 ℃; for 16h;

DOI:10.1021/ja0612549

upstream raw materials:

N-[2-(1-benzyl-1H-indol-3-yl)ethyl]-1H-imidazole-1-carboxamide

methyl hydrazino(oxo)acetate

N-benzyltryptamine

Downstream raw materials:

methyl 5-[2-(1-benzyl-1H-indol-3-yl)ethylamino]-1,3,4-oxadiazole-2-carboxylate

5-[2-(1-benzyl-1H-indol-3-yl)ethylamino]-1,3,4-oxadiazole-2-carbonitrile

5-[2-(1-benzyl-1H-indol-3-yl)ethylamino]-1,3,4-oxadiazole-2-carboxamide

N-[2-(1-benzyl-1H-indol-3-yl)ethyl]-N-(5-cyano-1,3,4-oxadiazol-2-yl)pent-4-enamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 909707-94-4 methyl 2-{2-[2-(1-benzyl-1H-indol-3-yl)ethylcarbamoyl]hydrazino}-2-oxoacetate

Send

Send

Metric Ton KG G Pound L ML

Send

Send