6-chloro-N,N-diethylpyridine-3-sulfonamide

Base Information

Chemical Name:6-chloro-N,N-diethylpyridine-3-sulfonamide
CAS No.:54864-87-8
Molecular Formula:C9H13ClN2O2S
Molecular Weight:248.73
Hs Code.:2935009090
DSSTox Substance ID:DTXSID50368647
Wikidata:Q82155349
ChEMBL ID:CHEMBL1541670
Mol file:54864-87-8.mol

Synonyms:54864-87-8;6-chloro-N,N-diethylpyridine-3-sulfonamide;6-Chloro-pyridine-3-sulfonic acid diethylamide;Enamine_005901;MLS000775799;CHEMBL1541670;SCHEMBL17645850;DTXSID50368647;OHBWIMRJRWBVEZ-UHFFFAOYSA-N;HMS1410M05;HMS2713N12;MFCD03504890;AKOS000118681;IDI1_008136;SMR000369365;CS-0220287;FT-0745378;EN300-06269;Z45516196

Suppliers and Price of 6-chloro-N,N-diethylpyridine-3-sulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6-Chloro-N,N-diethylpyridine-3-sulfonamide 97%
1g
$ 564.00

American Custom Chemicals Corporation
6-CHLORO-PYRIDINE-3-SULFONIC ACID DIETHYLAMIDE 95.00%
2.5G
$ 1473.14

American Custom Chemicals Corporation
6-CHLORO-PYRIDINE-3-SULFONIC ACID DIETHYLAMIDE 95.00%
1G
$ 983.52

American Custom Chemicals Corporation
6-CHLORO-PYRIDINE-3-SULFONIC ACID DIETHYLAMIDE 95.00%
5G
$ 1928.08

AK Scientific
6-Chloro-N,N-diethylpyridine-3-sulfonamide
10g
$ 1498.00

AK Scientific
6-Chloro-N,N-diethylpyridine-3-sulfonamide
500mg
$ 344.00

Total 4 raw suppliers

Chemical Property of 6-chloro-N,N-diethylpyridine-3-sulfonamide

Chemical Property:

Vapor Pressure:1.79E-05mmHg at 25°C
Melting Point:87-88 °C
Boiling Point:363.5°C at 760 mmHg
PKA:-2.40±0.10(Predicted)
Flash Point:173.7°C
PSA：58.65000
Density:1.287g/cm³
LogP:2.84630
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:248.0386265
Heavy Atom Count:15
Complexity:285

Purity/Quality:

99% ^*data from raw suppliers

6-Chloro-N,N-diethylpyridine-3-sulfonamide 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)S(=O)(=O)C1=CN=C(C=C1)Cl

Technology Process of 6-chloro-N,N-diethylpyridine-3-sulfonamide

There total 3 articles about 6-chloro-N,N-diethylpyridine-3-sulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6684-39-5
2-chloropyridine-5-sulfonyl chloride

: 109-89-7
diethylamine

: 54864-87-8
6-chloro-N,N-diethylpyridine-3-sulfonamide

Guidance literature:: With acetone; Kuehlung;
DOI:10.1002/hlca.193902201114

Reference yield:

: 53939-30-3
5-bromo-2-chloropyridine

: 54864-87-8
6-chloro-N,N-diethylpyridine-3-sulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium; dibutylmagnesium / tetrahydrofuran / -10 °C / Inert atmosphere

1.2: -10 - 10 °C

2.1: tetrahydrofuran; toluene / 0.5 h / 10 °C

With n-butyllithium; dibutylmagnesium; In tetrahydrofuran; toluene;
DOI:10.1055/s-0030-1259953

Reference yield:

: 5350-93-6
6-Chloro-pyridin-3-ylamine

: 54864-87-8
6-chloro-N,N-diethylpyridine-3-sulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride; thionyl chloride; copper(l) chloride; sodium nitrite / water / -5 - 7 °C

2: triethylamine / dichloromethane / 16 h / 0 - 20 °C

With hydrogenchloride; thionyl chloride; triethylamine; copper(l) chloride; sodium nitrite; In dichloromethane; water;