Technology Process of C27H31N7O7S
There total 7 articles about C27H31N7O7S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
di-isopropyl azodicarboxylate; triphenylphosphine;
In
tetrahydrofuran; N,N-dimethyl-formamide;
at 70 ℃;
for 2h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium carbonate / N,N-dimethyl-formamide / 3 h / 80 °C
2: hydrogenchloride / 1,4-dioxane
3: triethylamine / dichloromethane / 1 h / 0 °C / Inert atmosphere
4: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran; N,N-dimethyl-formamide / 2 h / 70 °C
With
hydrogenchloride; di-isopropyl azodicarboxylate; potassium carbonate; triethylamine; triphenylphosphine;
In
tetrahydrofuran; 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide;
4: |Mitsunobu Displacement;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: N-ethyl-N,N-diisopropylamine / acetonitrile / Reflux
2: dmap; triethylamine / tetrahydrofuran / 2 h / Reflux
3: potassium phosphate; tetrakis(triphenylphosphine) palladium(0); XPhos / 1,4-dioxane; water / 2 h / 80 °C / Inert atmosphere
4: potassium carbonate / N,N-dimethyl-formamide / 3 h / 80 °C
5: hydrogenchloride / 1,4-dioxane
6: triethylamine / dichloromethane / 1 h / 0 °C / Inert atmosphere
7: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran; N,N-dimethyl-formamide / 2 h / 70 °C
With
hydrogenchloride; dmap; potassium phosphate; tetrakis(triphenylphosphine) palladium(0); di-isopropyl azodicarboxylate; potassium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine; triphenylphosphine; XPhos;
In
tetrahydrofuran; 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
3: |Suzuki Coupling / 7: |Mitsunobu Displacement;