Technology Process of C19H18F2O2
There total 8 articles about C19H18F2O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
lithium hexamethyldisilazane;
In
tetrahydrofuran;
- Guidance literature:
-
With
lithium hexamethyldisilazane;
In
tetrahydrofuran;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: triethylamine; tris-(o-tolyl)phosphine / palladium diacetate / N,N-dimethyl-formamide / 110 °C / Inert atmosphere; Sealed
2.1: potassium hydroxide / diethyl ether; water / 0.03 h / 0 °C
2.2: 4 h / 0 - 5 °C
3.1: potassium carbonate / N,N-dimethyl-formamide / 20 °C
4.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C
5.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / -78 °C
6.1: lithium hexamethyldisilazane / tetrahydrofuran
With
lithium aluminium tetrahydride; oxalyl dichloride; potassium carbonate; dimethyl sulfoxide; triethylamine; tris-(o-tolyl)phosphine; potassium hydroxide; lithium hexamethyldisilazane;
palladium diacetate;
In
tetrahydrofuran; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide;
5.1: Swern Oxidation;