2-2-(2,4-dimethoxyphenyl)-3-(2-nitrobenzensulfenyl)-4⁽⁵⁾-phenyl-5(R)-oxazolidine carboxylic acid 10-deacetyl-7,10-bis-trichloroacetylbaccatin III 13-yl-ester

Base Information

• Chemical Name: 2-2-(2,4-dimethoxyphenyl)-3-(2-nitrobenzensulfenyl)-4⁽⁵⁾-phenyl-5(R)-oxazolidine carboxylic acid 10-deacetyl-7,10-bis-trichloroacetylbaccatin III 13-yl-ester
• CAS No.: 881844-47-9
• Molecular Formula: C₅₇H₅₄Cl₆N₂O₁₈S
• Molecular Weight: 1299.84

Synonyms:2-2-(2,4-dimethoxyphenyl)-3-(2-nitrobenzensulfenyl)-4⁽⁵⁾-phenyl-5(R)-oxazolidine carboxylic acid 10-deacetyl-7,10-bis-trichloroacetylbaccatin III 13-yl-ester

Chemical Property of 2-2-(2,4-dimethoxyphenyl)-3-(2-nitrobenzensulfenyl)-4⁽⁵⁾-phenyl-5(R)-oxazolidine carboxylic acid 10-deacetyl-7,10-bis-trichloroacetylbaccatin III 13-yl-ester

Chemical Property:

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Technology Process of 2-2-(2,4-dimethoxyphenyl)-3-(2-nitrobenzensulfenyl)-4⁽⁵⁾-phenyl-5(R)-oxazolidine carboxylic acid 10-deacetyl-7,10-bis-trichloroacetylbaccatin III 13-yl-ester

There total 1 articles about 2-2-(2,4-dimethoxyphenyl)-3-(2-nitrobenzensulfenyl)-4⁽⁵⁾-phenyl-5(R)-oxazolidine carboxylic acid 10-deacetyl-7,10-bis-trichloroacetylbaccatin III 13-yl-ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

10-deacetylbaccatin III 7,10-bis-trichloroacetate (289703-22-6) + 2-(2,4-dimethoxyphenyl)-3-(2-nitrobenzenesulfenyl)-4(S)-phenyl-5(R)-oxazolidinecarboxylic acid → 2-2-(2,4-dimethoxyphenyl)-3-(2-nitrobenzensulfenyl)-4(5)-phenyl-5(R)-oxazolidine carboxylic acid 10-deacetyl-7,10-bis-trichloroacetylbaccatin III 13-yl-ester (881844-47-9)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 1h;

Reference yield: 84.0%

2-2-(2,4-dimethoxyphenyl)-3-(2-nitrobenzensulfenyl)-4(5)-phenyl-5(R)-oxazolidine carboxylic acid 10-deacetyl-7,10-bis-trichloroacetylbaccatin III 13-yl-ester (881844-47-9) → 2-2-(2,4-dimethoxyphenyl)-3-(2-nitrobenzensulfenyl)-4(5)-phenyl-5(R)-oxazolidine carboxylic acid 10-deacetylbaccatin III 13-yl-ester (881844-48-0)

Guidance literature:

With ammonium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 2.08333h;

upstream raw materials:

10-deacetylbaccatin III 7,10-bis-trichloroacetate

Downstream raw materials:

2-2-(2,4-dimethoxyphenyl)-3-(2-nitrobenzensulfenyl)-4⁽⁵⁾-phenyl-5(R)-oxazolidine carboxylic acid 10-deacetylbaccatin III 13-yl-ester

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