Technology Process of methyl 1,2,4-tri-O-benzoyl-3-O-benzyl-β-L-idopyranurate
There total 1 articles about methyl 1,2,4-tri-O-benzoyl-3-O-benzyl-β-L-idopyranurate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
pyridine; dmap;
In
dichloromethane;
at -40 - 20 ℃;
DOI:10.1021/jo400467g
- Guidance literature:
-
methyl 1,2,4-tri-O-benzoyl-3-O-benzyl-β-L-idopyranurate;
With
hydrogen bromide;
In
dichloromethane; acetic acid;
at 0 ℃;
for 3h;
n-Pent-4-enyl alcohol;
With
2,6-dimethylpyridine;
In
dichloromethane;
at 20 ℃;
for 20h;
Inert atmosphere;
DOI:10.1021/jo400467g
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: hydrogen bromide / dichloromethane; acetic acid / 3 h / 0 °C
1.2: 20 h / 20 °C / Inert atmosphere
2.1: trimethyltin(IV) hydroxide / toluene / 1 h / 100 °C / Microwave irradiation
2.2: 60 °C / Microwave irradiation
3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane / 5 h / 20 °C
4.1: N-iodo-succinimide; trimethylsilyl trifluoromethanesulfonate / dichloromethane / 0 °C
5.1: hydrazinium monoacetate / dichloromethane; methanol
With
dmap; N-iodo-succinimide; trimethylsilyl trifluoromethanesulfonate; hydrogen bromide; hydrazinium monoacetate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trimethyltin(IV) hydroxide;
In
methanol; dichloromethane; acetic acid; toluene;
DOI:10.1021/jo400467g
