7-Cyclohexyl-2,2-dimethyl-3-vinyl-hept-6-ynoic acid ethyl ester

Base Information

• Chemical Name: 7-Cyclohexyl-2,2-dimethyl-3-vinyl-hept-6-ynoic acid ethyl ester
• CAS No.: 211820-31-4
• Molecular Formula: C₁₉H₃₀O₂
• Molecular Weight: 290.446
• Mol file: 211820-31-4.mol

Synonyms:7-Cyclohexyl-2,2-dimethyl-3-vinyl-hept-6-ynoic acid ethyl ester

Chemical Property of 7-Cyclohexyl-2,2-dimethyl-3-vinyl-hept-6-ynoic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-Cyclohexyl-2,2-dimethyl-3-vinyl-hept-6-ynoic acid ethyl ester

There total 1 articles about 7-Cyclohexyl-2,2-dimethyl-3-vinyl-hept-6-ynoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

7-Cyclohexyl-3-vinyl-hept-6-ynoic acid ethyl ester + methyl iodide (74-88-4) → 7-Cyclohexyl-2,2-dimethyl-3-vinyl-hept-6-ynoic acid ethyl ester (211820-31-4)

Guidance literature:

With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium diisopropyl amide; In tetrahydrofuran;

DOI:10.1021/jo980521t

Reference yield: 90.0%

7-Cyclohexyl-2,2-dimethyl-3-vinyl-hept-6-ynoic acid ethyl ester (211820-31-4) → 7-Cyclohexyl-2,2-dimethyl-3-vinyl-hept-6-yn-1-ol (211820-32-5)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran;

DOI:10.1021/jo980521t

Reference yield:

7-Cyclohexyl-2,2-dimethyl-3-vinyl-hept-6-ynoic acid ethyl ester (211820-31-4) → {(3aS,6aR)-4-[1-Cyclohexyl-meth-(E)-ylidene]-1,1-dimethyl-octahydro-pentalen-2-ylmethyl}-phenyl-silane

Guidance literature:

Multi-step reaction with 4 steps

1: 90 percent / LAH / tetrahydrofuran

2: 85 percent / pyr*SO₃, DMSO, Et₃N / CH₂Cl₂

3: 89 percent / t-BuOK / diethyl ether

4: 76 percent / (C₅Me₅)2YCH₃*THF / cyclohexane / 18 h / Ambient temperature

With lithium aluminium tetrahydride; potassium tert-butylate; sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine; (C₅Me₅)2YCH₃*THF; In tetrahydrofuran; diethyl ether; dichloromethane; cyclohexane;

DOI:10.1021/jo980521t

upstream raw materials:

methyl iodide

Downstream raw materials:

7-Cyclohexyl-2,2-dimethyl-3-vinyl-hept-6-yn-1-ol

(6,6-Dimethyl-5-vinyl-oct-7-en-1-ynyl)-cyclohexane

7-Cyclohexyl-2,2-dimethyl-3-vinyl-hept-6-ynal