dimethylcarbamic acid 3-amino-2-iodophenyl ester

Base Information

• Chemical Name: dimethylcarbamic acid 3-amino-2-iodophenyl ester
• CAS No.: 916445-87-9
• Molecular Formula: C₉H₁₁IN₂O₂
• Molecular Weight: 306.103
• Mol file: 916445-87-9.mol

Synonyms:dimethylcarbamic acid 3-amino-2-iodophenyl ester

Chemical Property of dimethylcarbamic acid 3-amino-2-iodophenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of dimethylcarbamic acid 3-amino-2-iodophenyl ester

There total 2 articles about dimethylcarbamic acid 3-amino-2-iodophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

dimethylcarbamic acid 2-iodo-3-nitrophenyl ester (916445-83-5) → dimethylcarbamic acid 3-amino-2-iodophenyl ester (916445-87-9)

Guidance literature:

With iron; acetic acid; In ethanol; at 60 ℃; for 4h;

DOI:10.1021/jo061660a

Reference yield:

2-iodo-3-nitrophenol (197243-48-4) → dimethylcarbamic acid 3-amino-2-iodophenyl ester (916445-87-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / Et₃N; DMAP / CH₂Cl₂ / 0 - 20 °C

2: 93 percent / Fe; AcOH / ethanol / 4 h / 60 °C

With dmap; iron; acetic acid; triethylamine; In ethanol; dichloromethane;

DOI:10.1021/jo061660a

Reference yield: 97.0%

dimethylcarbamic acid 3-amino-2-iodophenyl ester (916445-87-9) + 3-[1-[2-(4-Methoxy-phenoxymethyl)-phenyl]-meth-(E)-ylidene]-dihydro-furan-2-one → dimethylcarbamic acid 3-{4-hydroxy-2-[2-(4-methoxyphenoxymethyl)benzylidene]butyrylamino}-2-iodophenyl ester

Guidance literature:

With trimethylaluminum; In hexane; dichloromethane; at 0 - 20 ℃;

DOI:10.1021/jo061660a

upstream raw materials:

dimethylcarbamic acid 2-iodo-3-nitrophenyl ester

2-iodo-3-nitrophenol

Downstream raw materials:

C₃₃H₃₄N₂O₇