tert-butyl-[3-(4-methoxy-benzyloxy)-1-methoxymethyl-propoxy]-diphenyl-silane

Base Information

• Chemical Name: tert-butyl-[3-(4-methoxy-benzyloxy)-1-methoxymethyl-propoxy]-diphenyl-silane
• CAS No.: 398127-59-8
• Molecular Formula: C₂₉H₃₈O₄Si
• Molecular Weight: 478.704

Synonyms:tert-butyl-[3-(4-methoxy-benzyloxy)-1-methoxymethyl-propoxy]-diphenyl-silane

Chemical Property of tert-butyl-[3-(4-methoxy-benzyloxy)-1-methoxymethyl-propoxy]-diphenyl-silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl-[3-(4-methoxy-benzyloxy)-1-methoxymethyl-propoxy]-diphenyl-silane

There total 2 articles about tert-butyl-[3-(4-methoxy-benzyloxy)-1-methoxymethyl-propoxy]-diphenyl-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S,4S)-tert-butyl-[2-(4-methoxy-phenyl)-[1,3]dioxan-4-ylmethoxy]-diphenyl-silane (231299-11-9) → tert-butyl-[3-(4-methoxy-benzyloxy)-1-methoxymethyl-propoxy]-diphenyl-silane (398127-59-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: BH₃*NMe₃ complex / tetrahydrofuran / 0.5 h / 20 °C

1.2: 55 percent / AlCl₃ / tetrahydrofuran / -15 - 0 °C

2.1: NaH / tetrahydrofuran / 0.25 h / Heating; cooling

2.2: tetrabutylammonium iodide / Heating

With trimethylamine-borane; sodium hydride; In tetrahydrofuran;

DOI:10.1021/ol016991i

Reference yield:

(2S)-tert-butyl-[2-hydroxy-4-(4-methoxy-benzyloxy)-butoxy]-diphenyl-silane + methyl iodide (74-88-4) → tert-butyl-[3-(4-methoxy-benzyloxy)-1-methoxymethyl-propoxy]-diphenyl-silane (398127-59-8) + (2S)-tert-butyl-[2-methoxy-4-(4-methoxy-benzyloxy)-butoxy]-diphenyl-silane (398127-56-5)

Guidance literature:

(2S)-tert-butyl-[2-hydroxy-4-(4-methoxy-benzyloxy)-butoxy]-diphenyl-silane; With sodium hydride; In tetrahydrofuran; for 0.25h; Heating; cooling;

methyl iodide; With tetra-(n-butyl)ammonium iodide; Further stages. Title compound not separated from byproducts.; Heating;

DOI:10.1021/ol016991i

Reference yield:

tert-butyl-[3-(4-methoxy-benzyloxy)-1-methoxymethyl-propoxy]-diphenyl-silane (398127-59-8) + (2S)-tert-butyl-[2-methoxy-4-(4-methoxy-benzyloxy)-butoxy]-diphenyl-silane (398127-56-5) → (S)-4-(4-Hydroxymethyl-benzyloxy)-1-methoxy-butan-2-ol + (2S)-2-methoxy-4-(4-methoxy-benzyloxy)-butan-1-ol

Guidance literature:

With tetrabutyl ammonium fluoride; acetic acid; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1021/ol016991i

upstream raw materials:

methyl iodide

(2S,4S)-tert-butyl-[2-(4-methoxy-phenyl)-[1,3]dioxan-4-ylmethoxy]-diphenyl-silane

Downstream raw materials:

(1R,2S)-1-[1-ethylsulfanyl-2-methoxy-4-(4-methoxy-benzyloxy)-butyl]-1H-pyrimidine-2,4-dione

(1S,2S)-1-[1-ethylsulfanyl-2-methoxy-4-(4-methoxy-benzyloxy)-butyl]-1H-pyrimidine-2,4-dione

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 398127-59-8 tert-butyl-[3-(4-methoxy-benzyloxy)-1-methoxymethyl-propoxy]-diphenyl-silane

Send

Send

Metric Ton KG G Pound L ML

Send

Send