4-(2-Hydroxypropyl)benzaldehyde

Base Information

Chemical Name:4-(2-Hydroxypropyl)benzaldehyde
CAS No.:1357255-97-0
Molecular Formula:C₁₀H₁₂O₂
Molecular Weight:164.204
Hs Code.:
European Community (EC) Number:863-383-0
Nikkaji Number:J2.967.734D

Synonyms:4-(2-hydroxypropyl)benzaldehyde;1357255-97-0;SCHEMBL1249267;Benzaldehyde, 4-(2-hydroxypropyl)-;EN300-5213039;Z1511913303

Suppliers and Price of 4-(2-Hydroxypropyl)benzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 4-(2-Hydroxypropyl)benzaldehyde

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:164.083729621
Heavy Atom Count:12
Complexity:137

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(CC1=CC=C(C=C1)C=O)O

Technology Process of 4-(2-Hydroxypropyl)benzaldehyde

There total 4 articles about 4-(2-Hydroxypropyl)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 630392-43-7
1-(4-formylphenyl)propan-2-one

: 1357255-97-0
4-(2-hydroxypropyl) benzaldehyde

Guidance literature:: 1-(4-formylphenyl)propan-2-one; With trimethylsilyl trifluoromethanesulfonate; triphenylphosphine; In dichloromethane; at 20 ℃; for 1h; Inert atmosphere;

With borane-THF; In tetrahydrofuran; dichloromethane; at -40 - -20 ℃; for 3h; Inert atmosphere;

With water; sodium hydrogencarbonate; In tetrahydrofuran; methanol; dichloromethane; at 40 ℃; for 2h; chemoselective reaction;
DOI:10.1002/anie.201106046

Reference yield: 55.0%

: 1122-91-4
4-bromo-benzaldehyde

: 75-56-9,16033-71-9
methyloxirane

: 1357255-97-0
4-(2-hydroxypropyl) benzaldehyde

: 1512868-96-0
C₁₀H₁₂O₂

Guidance literature:: With pyridine; 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; 4,4'-bipyridine; NiI₂*3.9H₂O; triethylamine hydrochloride; sodium iodide; zinc; at 20 ℃; for 12h;
DOI:10.1021/ja410704d

Reference yield:

: 1305324-15-5
C₁₃H₁₈O₂

: 1357255-97-0
4-(2-hydroxypropyl) benzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: ozone / dichloromethane / 2.5 h / -78 °C

1.2: -78 - 20 °C

2.1: trimethylsilyl trifluoromethanesulfonate; triphenylphosphine / dichloromethane / 1 h / 20 °C / Inert atmosphere

2.2: 3 h / -40 - -20 °C / Inert atmosphere

2.3: 2 h / 40 °C

With trimethylsilyl trifluoromethanesulfonate; ozone; triphenylphosphine; In dichloromethane;
DOI:10.1002/anie.201106046