1-Bromo-4-(dimethoxymethyl)benzene

Base Information

• Chemical Name: 1-Bromo-4-(dimethoxymethyl)benzene
• CAS No.: 24856-58-4
• Molecular Formula: C9H11BrO2
• Molecular Weight: 231.089
• Hs Code.: 2909309090
• European Community (EC) Number: 918-110-0,629-494-1
• DSSTox Substance ID: DTXSID70350882
• Nikkaji Number: J314.386D
• Wikidata: Q72451464
• Mol file: 24856-58-4.mol

Synonyms:4-Bromobenzaldehyde dimethyl acetal;1-bromo-4-(dimethoxymethyl)benzene;24856-58-4;MFCD01320499;4-bromo-benzaldehyde dimethyl acetal;SCHEMBL6502;(4-Bromophenyl)dimethoxymethane;DTXSID70350882;1-bromo-4-dimethoxymethyl benzene;1-bromo-4-dimethoxymethyl-benzene;4-bromobenzaldehyde dimethyl ketal;4-bromo-benzaldehyde dimethyl ketal;AMY30000;AKOS015889258;4-BROMOBENZALDEHYDEDIMETHYLACETAL;Benzene, 1-bromo-4-(dimethoxymethyl)-;4-Bromobenzaldehyde dimethyl acetal, 98%;PS-11664;SY024052;B5819;CS-0150667;FT-0699671;D84237;A877781;J-015703

Chemical Property of 1-Bromo-4-(dimethoxymethyl)benzene

Chemical Property:

• Vapor Pressure: 0.0612mmHg at 25°C
• Refractive Index: n20/D 1.532(lit.)
• Boiling Point: 239.7 °C at 760 mmHg
• Flash Point: 91.3 °C
• PSA: 18.46000
• Density: 1.372 g/cm³
• LogP: 2.74050
• Storage Temp.: Inert atmosphere,Room Temperature
• Water Solubility.: Insoluble in water.
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 229.99424
• Heavy Atom Count: 12
• Complexity: 118

Purity/Quality:

99.9% ^*data from raw suppliers

4-Bromobenzaldehyde dimethyl acetal ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(C1=CC=C(C=C1)Br)OC
• Uses: 4-Bromobenzaldehyde dimethyl acetal, is used to produce other chemicals, it is used to produce 1-Bromo-4-bromomethyl-benzene at ambient temperature. 4-Bromobenzaldehyde diethyl acetal may be used in the synthesis of [2-(4-dimethoxymethylphenyl)-vinyl]-trimethyl-silane and di(4-formylphenyl)diphenylsilane.

Technology Process of 1-Bromo-4-(dimethoxymethyl)benzene

There total 8 articles about 1-Bromo-4-(dimethoxymethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-bromo-benzaldehyde (1122-91-4) + trimethyl orthoformate (149-73-5) → 1,1-dimethoxy-1-(4-bromophenyl)methane (24856-58-4)

Guidance literature:

Yb-Amberlyst XN-1010; In dichloromethane;

DOI:10.1021/jo961933+

Reference yield: 99.0%

methanol (67-56-1) + 4-bromo-benzaldehyde (1122-91-4) → 1,1-dimethoxy-1-(4-bromophenyl)methane (24856-58-4)

Guidance literature:

Ce⁽³⁺⁾-mont; at 25 ℃; for 12h;

DOI:10.1021/jo00118a021

Reference yield: 91.7%

methanol (67-56-1) + 4-bromo-benzaldehyde (1122-91-4) + trimethyl orthoformate (149-73-5) → 1,1-dimethoxy-1-(4-bromophenyl)methane (24856-58-4)

Guidance literature:

With povidone-iodine; at 30 ℃; for 3h; Green chemistry;

DOI:10.1016/j.tet.2021.132250

upstream raw materials:

4-bromo-benzaldehyde

trimethyl orthoformate

methanol

para-bromotoluene

Downstream raw materials:

4-methoxycarbonylphenyl bromide

trimethyl 4-bromobenzoate

1-Bromo-4-(1,3,3-trimethoxy-propyl)-benzene

(1S,2R,5R,6R,7S,8R,12S,13S,17R)-15-(4-Bromo-phenyl)-7-hydroxy-2,5,6,8,12,17-hexamethyl-4,14,16-trioxa-bicyclo[11.3.1]heptadecane-3,9-dione