4-oxopentyl cyclohex-1-enecarboxylate

Base Information

• Chemical Name: 4-oxopentyl cyclohex-1-enecarboxylate
• CAS No.: 1449522-68-2
• Molecular Formula: C₁₂H₁₈O₃
• Molecular Weight: 210.273
• Mol file: 1449522-68-2.mol

Synonyms:4-oxopentyl cyclohex-1-enecarboxylate

Chemical Property of 4-oxopentyl cyclohex-1-enecarboxylate

Chemical Property:

Purity/Quality:

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Technology Process of 4-oxopentyl cyclohex-1-enecarboxylate

There total 1 articles about 4-oxopentyl cyclohex-1-enecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

5-Hydroxy-2-pentanone (1071-73-4) + cyclohexene-1-carboxylic acid (636-82-8) → 4-oxopentyl cyclohex-1-enecarboxylate (1449522-68-2)

Guidance literature:

With dmap; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1039/c3cc44149k

Reference yield:

4-oxopentyl cyclohex-1-enecarboxylate (1449522-68-2) + bis(pinacol)diborane (73183-34-3) → 4-oxopentyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-1-enecarboxylate (1449522-58-0)

Guidance literature:

bis(pinacol)diborane; With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; triphenyl-arsane; In octane; at 20 ℃; for 0.166667h; Inert atmosphere;

4-oxopentyl cyclohex-1-enecarboxylate; In octane; at 120 ℃; for 2h; chemoselective reaction; Inert atmosphere;

DOI:10.1039/c3cc44149k

upstream raw materials:

5-Hydroxy-2-pentanone

cyclohexene-1-carboxylic acid

Downstream raw materials:

4-oxopentyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-1-enecarboxylate