MK-5932

Base Information

Chemical Name:MK-5932
CAS No.:1021539-02-5
Molecular Formula:C₂₆H₂₅F₂N₃O₂
Molecular Weight:449.5
Hs Code.:

Synonyms:MK-5932

Suppliers and Price of MK-5932

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of MK-5932

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of MK-5932

There total 6 articles about MK-5932 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1021539-61-6
C₂₆H₂₁F₂N₃O₂

: 1021539-02-5
MK-5932

Guidance literature:: With hydrogen; palladium(II) hydroxide/carbon; In 2-methyltetrahydrofuran; for 6h; under 760.051 Torr;

Reference yield: 76.0%

: 1021539-51-4
5-fluoro-2-{2-[(4aS,5R)-1-(4-fluorophenyl)-5-hydroxy-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl]ethyl}benzoic acid

: 1021539-02-5
MK-5932

Guidance literature:: With ammonia; N-ethyl-N,N-diisopropylamine; HATU; In 1,4-dioxane; N,N-dimethyl-formamide; for 1h;

Reference yield:

: 754235-83-1
(4aS,5R)-5-ethynyl-1-(4-fluorophenyl)-4a-methyl-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-ol

: 1021539-02-5
MK-5932

Guidance literature:: Multi-step reaction with 4 steps

1: copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; diisopropylamine / tetrahydrofuran / 1 h / 20 - 80 °C

2: palladium 10% on activated carbon; hydrogen / ethyl acetate / 20 °C

3: water; sodium hydroxide / ethanol / 1 h / 100 °C

4: ammonia; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 1 h / 20 °C

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; palladium 10% on activated carbon; ammonia; water; hydrogen; diisopropylamine; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In tetrahydrofuran; ethanol; ethyl acetate; N,N-dimethyl-formamide; 1: Sonogashira coupling;
DOI:10.1016/j.bmc.2011.10.054