3-O-(4-methoxyphenyl)propane-1-thiol

Base Information

• Chemical Name: 3-O-(4-methoxyphenyl)propane-1-thiol
• CAS No.: 864389-74-2
• Molecular Formula: C₁₀H₁₄O₂S
• Molecular Weight: 198.286
• Mol file: 864389-74-2.mol

Synonyms:3-O-(4-methoxyphenyl)propane-1-thiol

Chemical Property of 3-O-(4-methoxyphenyl)propane-1-thiol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-O-(4-methoxyphenyl)propane-1-thiol

There total 2 articles about 3-O-(4-methoxyphenyl)propane-1-thiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

allyl (4-methoxyphenyl) ether (13391-35-0) → 3-O-(4-methoxyphenyl)propane-1-thiol (864389-74-2)

Guidance literature:

allyl (4-methoxyphenyl) ether; With tiolacetic acid; In cyclohexane; for 16h; Irradiation;

With potassium hydroxide; In methanol; at 20 ℃; for 2h;

DOI:10.1002/adsc.202100088

Reference yield:

4-methoxy-phenol (150-76-5) + 1,3-dibromo-propane (109-64-8) → 3-O-(4-methoxyphenyl)propane-1-thiol (864389-74-2)

Guidance literature:

4-methoxy-phenol; 1,3-dibromo-propane;

With thiourea;

DOI:10.1021/jp2091363

Reference yield: 48.0%

3,3,3-trifluoro-2-phenylpropene (384-64-5) + 3-O-(4-methoxyphenyl)propane-1-thiol (864389-74-2) → 1-[(6,6-difluoro-5-phenylhex-5-en-1-yl)oxy]-4-methoxybenzene

Guidance literature:

With chloro-trimethyl-silane; [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-N1,N1′]bis{3,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl-κN]phenyl-κC}iridium(III) hexafluorophosphate; benzylzinc chloride; triphenylphosphine; In tetrahydrofuran; dichloromethane; for 4h; Irradiation;

DOI:10.1002/adsc.202100088

upstream raw materials:

4-methoxy-phenol

1,3-dibromo-propane

allyl (4-methoxyphenyl) ether

Downstream raw materials:

mono(6-deoxy-6-thio-(1-propane-3-O-(4-methoxyphenyl)))β-cyclodextrin