Chemical Property of 3,4-Dihydrocoumarin
Chemical Property:
- Appearance/Colour:Colorless to pale yellow clear liquid
- Vapor Pressure:0.00624mmHg at 25°C
- Melting Point:24-25 °C(lit.)
- Refractive Index:n20/D 1.556(lit.)
- Boiling Point:272 °C at 760 mmHg
- Flash Point:108.4 °C
- PSA：26.30000
- Density:1.169 g/cm3
- LogP:1.53820
- Storage Temp.:Store below +30°C.
- Solubility.:Chloroform, Methanol (Sparingly)
- Water Solubility.:insoluble
- XLogP3:1.6
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:2
- Rotatable Bond Count:0
- Exact Mass:148.052429494
- Heavy Atom Count:11
- Complexity:165
- Purity/Quality:
-
99% *data from raw suppliers
Hydrocoumarin *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xn
- Hazard Codes:Xn
- Statements:
22-36/37/38
- Safety Statements:
26-36
- MSDS Files:
-
SDS file from LookChem
Useful:
- Chemical Classes:Other Classes -> Other Organic Compounds
- Canonical SMILES:C1CC(=O)OC2=CC=CC=C21
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Description
With a sweet, creamy, and herbal, fragrance, with a slightly burnt taste, dihydrocoumarin (DHC) is used as a flavoring agent in food, tobacco, soap, and perfume, etc. Its exotic flavor is well suited for caramel, nuts, dairy, vanilla, tropical fruit, and alcohol. It is a eukaryotic metabolite found in tonka beans grown in northern South America, from which it was isolated as early as the 1820s, as well as sweet clover. Other uses include as an organic solvent and pharmaceutical intermediary. It has been shown to influence the epigenetic process of human cells in vitro.
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Uses
Hydrocoumarin can be used as a reagent to prepare splitomicin analogs as inhibitors of Sir2. Dihydrocoumarin may be used as an analytical reference standard for the determination of the analyte in guaco extracts and pharmaceutical preparations, and various plant extracts by chromatography-based techniques and capillary electrophoresis.
