N¹-(3-((3-(3-bromophenyl)-6-oxopyridazin-1(6H)-yl)methyl)phenyl)-N⁴,N⁴-diethylpiperidine-1,4-dicarboxamide

Base Information

• Chemical Name: N¹-(3-((3-(3-bromophenyl)-6-oxopyridazin-1(6H)-yl)methyl)phenyl)-N⁴,N⁴-diethylpiperidine-1,4-dicarboxamide
• CAS No.: 1443124-86-4
• Molecular Formula: C₂₈H₃₂BrN₅O₃
• Molecular Weight: 566.498

Synonyms:N¹-(3-((3-(3-bromophenyl)-6-oxopyridazin-1(6H)-yl)methyl)phenyl)-N⁴,N⁴-diethylpiperidine-1,4-dicarboxamide

Chemical Property of N¹-(3-((3-(3-bromophenyl)-6-oxopyridazin-1(6H)-yl)methyl)phenyl)-N⁴,N⁴-diethylpiperidine-1,4-dicarboxamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N¹-(3-((3-(3-bromophenyl)-6-oxopyridazin-1(6H)-yl)methyl)phenyl)-N⁴,N⁴-diethylpiperidine-1,4-dicarboxamide

There total 4 articles about N¹-(3-((3-(3-bromophenyl)-6-oxopyridazin-1(6H)-yl)methyl)phenyl)-N⁴,N⁴-diethylpiperidine-1,4-dicarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N-diethylpiperidine-4-carboxamide (1903-67-9) + bis(trichloromethyl) carbonate (32315-10-9) + C17H14BrN3O → N1-(3-((3-(3-bromophenyl)-6-oxopyridazin-1(6H)-yl)methyl)phenyl)-N4,N4-diethylpiperidine-1,4-dicarboxamide (1443124-86-4)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.ejmech.2013.01.056

Reference yield:

6-(3-bromo-phenyl)-2H-pyridazin-3-one (62902-65-2) → N1-(3-((3-(3-bromophenyl)-6-oxopyridazin-1(6H)-yl)methyl)phenyl)-N4,N4-diethylpiperidine-1,4-dicarboxamide (1443124-86-4)

Guidance literature:

Multi-step reaction with 3 steps

1: caesium carbonate / N,N-dimethyl-formamide / 3 h / 40 - 50 °C

2: acetic acid; iron / ethanol / 5 h / 120 °C

3: triethylamine / dichloromethane / 20 °C / Inert atmosphere

With iron; caesium carbonate; acetic acid; triethylamine; In ethanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.ejmech.2013.01.056

Reference yield:

C17H12BrN3O3 (899752-88-6) → N1-(3-((3-(3-bromophenyl)-6-oxopyridazin-1(6H)-yl)methyl)phenyl)-N4,N4-diethylpiperidine-1,4-dicarboxamide (1443124-86-4)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid; iron / ethanol / 5 h / 120 °C

2: triethylamine / dichloromethane / 20 °C / Inert atmosphere

With iron; acetic acid; triethylamine; In ethanol; dichloromethane;

DOI:10.1016/j.ejmech.2013.01.056

upstream raw materials:

6-(3-bromo-phenyl)-2H-pyridazin-3-one

C₁₇H₁₂BrN₃O₃

N,N-diethylpiperidine-4-carboxamide

bis(trichloromethyl) carbonate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1443124-86-4 N¹-(3-((3-(3-bromophenyl)-6-oxopyridazin-1(6H)-yl)methyl)phenyl)-N⁴,N⁴-diethylpiperidine-1,4-dicarboxamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send