2-(dimethylamino)benzyllithium

Base Information

• Chemical Name: 2-(dimethylamino)benzyllithium
• CAS No.: 64308-58-3
• Molecular Formula: C₉H₁₂LiN
• Molecular Weight: 141.142
• Mol file: 64308-58-3.mol

Synonyms:2-(dimethylamino)benzyllithium

Chemical Property of 2-(dimethylamino)benzyllithium

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(dimethylamino)benzyllithium

There total 1 articles about 2-(dimethylamino)benzyllithium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

diethyl ether (60-29-7,927820-24-4) + N,N-dimethyl-o-toluidine (609-72-3) → 2-(dimethylamino)benzyllithium (64308-58-3)

Guidance literature:

With n-butyllithium; In hexane;

Reference yield: 92.0%

6-Bromo-1-hexene (2695-47-8) + 2-(dimethylamino)benzyllithium (64308-58-3) → (2-Hept-6-enyl-phenyl)-dimethyl-amine (155933-58-7)

Guidance literature:

In diethyl ether; for 4h; Ambient temperature;

DOI:10.1021/ja00091a016

Reference yield: 88.5%

tetrahydrofuran (109-99-9,24979-97-3,77392-70-2) + samarium(III) chloride + N-phenylindeno[2,1-b]indolyl lithium + 2-(dimethylamino)benzyllithium (64308-58-3) → C39H38N3Sm

Guidance literature:

tetrahydrofuran; samarium(III) chloride; at 70 ℃; for 10h; Schlenk technique;

N-phenylindeno[2,1-b]indolyl lithium; In tetrahydrofuran; at -25 - 20 ℃; for 12h; Schlenk technique;

2-(dimethylamino)benzyllithium; In toluene; at -25 - 20 ℃; for 16h; Schlenk technique;

upstream raw materials:

diethyl ether

N,N-dimethyl-o-toluidine

Downstream raw materials:

(2-Hept-6-enyl-phenyl)-dimethyl-amine

C₆H₄(N(CH₃)2)CH₂Sn(CH₃)3

{(cyclopentadienyl)2(o-dimethylaminobenzyl)2Hf}

{(cyclopentadienyl)2(o-dimethylaminobenzyl)2Zr}